Originally: (of animal tissue or skin) hardened, thickened; = callous, adj. 1. In later use also Botany: bearing one or more callosities (cf. callous…

Of animal tissue: hardened, thickened, indurated; spec. (of the skin) having a thickened horny layer (stratum corneum), typically resulting from…

Characterized by hardened skin.

? Affected with callosity.

Incapable of producing or allowing the passage of perspiration. Also: incapable of being eliminated as perspiration or through the pores.

Of human or animal tissue: hardened, thickened, indurated; spec. (esp. of the skin of the hands and feet) having calluses. Also (of a broken…

Of a person, the heart, etc.: made hard, unfeeling, or callous.

Of skin (usually on hands or feet): calloused, roughened, thickened.

dialect. Callous or horny like a hoof.

having hands made horny by hard work.