cimetidinen.
/sʌɪˈmɛtɪdiːn/ Pharmacology.
An imidazole derivative, C10H16N6S, with histamine H2-receptor blocking properties, given (usually in tablet form as the hydrochloride) in the treatment of peptic ulcers.
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the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations treating or preventing specific ailments > [noun] > for ulcers
sucralfate1969
metiamide1973
Tagamet1974
cimetidine1975
ranitidine1979
1975 Brit. Jrnl. Pharmacol. 53 435 P/2 In male human volunteers cimetidine given intravenously has been shown to inhibit histamine- or pentagastrin-stimulated gastric secretion.
1977 Lancet 9 July 74/2 The third therapeutic approach involves antacids and drugs such as the H2-receptor blockers metiamide and cimetidine which inhibit gastric secretion.
1986 C. W. Thornber in C. A. Heaton Chem. Industry iv. 177 Cimetidine..is currently the world's top selling drug.
1989 Brit. Med. Jrnl. 6 May 1266/1 H2 receptor antagonists like cimetidine have reduced the need for hospital admission and for surgery in patients with uncomplicated duodenal ulcer.
This entry has not yet been fully updated (first published 1993; most recently modified version published online June 2018).
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n.1975