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单词 clonazepam
释义

clonazepamn.

Brit. /ˌkləʊˈneɪzᵻpam/, /ˌkləʊˈnazᵻpam/, U.S. /ˌkloʊˈnæzəˌpæm/
Origin: Probably formed within English, by compounding. Etymons: chloro- comb. form2, nitro- comb. form, -azepam comb. form.
Etymology: Probably < clo- (representing chloro- comb. form2) + n- (in nitro- comb. form), elements in the chemical name + -azepam comb. form.
Pharmacology.
A benzodiazepine with potent anticonvulsant used esp. in the treatment of epilepsy and other seizure disorders.Clonazepam is a derivative of nitrazepam. Chemical formula: C15H10ClN3O3.A proprietary name for this drug is Klonopin.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > sedatives, antispasmodics, etc. > [noun] > antispasmodic or anticonvulsant > specific substances or preparations
Dilantin1938
phenytoin1942
Artane1948
Mysoline1949
mephenesin1952
troxidone1952
primidone1953
acetazolamide1954
orphenadrine1957
tetrabenazine1958
ethosuximide1960
methsuximide1965
clonazepam1970
valproic1972
valproate1974
1970 Pharmacologist 12 219/1 Application of methods developed to study clonazepam, 5-(2-chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one, in the presence of minor motor seizures has produced evidence of anticonvulsant activity.
1993 S. J. Ettinger Pocket Compan. Textbk. Vet. Internal Med. xv. 45 If seizures cannot be controlled with either phenobarbital or primidone, concomitant use of..a long-acting benzodiazepine such as clonazepam..should be considered.
2006 Independent (Nexis) 26 Jan. (News section) 1 He had been prescribed clonazepam, an anti-anxiety drug that can cause depression.
This entry has been updated (OED Third Edition, September 2009; most recently modified version published online March 2022).
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n.1970
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