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单词 clopidogrel
释义

clopidogreln.

Brit. /klə(ʊ)ˈpɪdəɡrɛl/, U.S. /kloʊˈpɪdəˌɡrɛl/
Origin: Formed within English, by compounding. Etymons: ticlopidine n., -o- connective, English -grel.
Etymology: < -clopid- (in ticlopidine n.) + -o- connective + -grel, element occasionally used in names of drugs inhibiting platelet aggregation (earlier in oxagrelate , in which -agre- probably represents aggregate and -late is probably < carboxylate n.).
Pharmacology.
A drug that inhibits the aggregation of blood platelets, used chiefly to prevent thrombotic complications in patients with atherosclerosis.Chemical name: 5-[(2-chlorophenyl)methyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl acetate, C16H16ClNO2S.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations for treating specific parts > [noun] > for the blood > anti-coagulants
anti-coagulant1905
heparin1918
Tromexan1949
warfarin1950
phenindione1955
ticlopidine1975
clopidogrel1989
1989 USAN & USP Dict. Drug Names 142 Clopidogrel. C16H16ClNO2S... INN.
1998 Ann. Internal Med. 129 394 Clopidogrel was recently approved by the U.S. Food and Drug Administration for the reduction of ischemic events in patients with recent myocardial infarction.
2002 Times 11 Feb. ii. 18/1 Daily doses of aspirin and another anti-clotting drug called clopidogrel can dramatically increase life expectancy in people who have had a heart attack.
This is a new entry (OED Third Edition, June 2005; most recently modified version published online March 2022).
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n.1989
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