co-factorn.

Origin: Of multiple origins. Partly formed within English, by derivation. Partly formed within English, by clipping or shortening. Etymons: co- prefix, factor n.; English coenzyme factor.

Etymology: In sense 1 < co- prefix + factor n.; compare coefficient n. 2a. In sense 2 shortened < coenzyme factor (compare quot. 1937) < co-enzyme n. + factor n.Previous versions of the OED give the stress as: co-ˈfactor.

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1. Algebra. One of the several factors of a product; a coefficient.

2. Chemistry. (a) Any substance other than the substrate (as a co-enzyme or a metal ion) the presence of which is necessary for the activity of a particular enzyme; (b) (see quot. 1956); (formerly called co-enzyme factor).

ΚΠ

1937 Dewan & Green in Nature 25 Dec. 1098/1 A New Oxidation Catalyst... We have succeeded in resolving the so-called coenzyme oxidase into three insoluble components, (1) the coenzyme factor... The coenzyme factor catalyses the first oxidation.]

1945 Jrnl. Cellular & Compar. Physiol. 25 12 The virus T₄..is not effective in lysing such irradiated cells unless a co-factor such as tryptophane is present in the mixture to enhance its rate of adsorption on the host.

1949 Adv. in Enzymol. IX. 178 Certain ‘cofactors’, such as l-tryptophan, have the power of promoting adsorption of certain bacteriophages on their hosts.

1956 Blakiston's New Gould Med. Dict. (ed. 2) 265/2 Cofactor, in bacteriology, any amino acid which must be present in the medium to activate phage to adsorb host bacteria.

1958 M. Dixon & E. C. Webb Enzymes ix. 394 An additional substance besides the enzyme and substrate is required in many cases in order that the reaction may proceed. Such ‘cofactors’ are found unchanged at the end of the reaction and may therefore be regarded as an essential part of the catalytic mechanism. The majority of enzyme cofactors may be broadly divided into..(a) specific coenzymes..(b) activators.

This entry has not yet been fully updated (first published 1989; most recently modified version published online June 2021).

单词	co-factor
释义	co-factorn. Origin: Of multiple origins. Partly formed within English, by derivation. Partly formed within English, by clipping or shortening. Etymons: co- prefix, factor n.; English coenzyme factor. Etymology: In sense 1 < co- prefix + factor n.; compare coefficient n. 2a. In sense 2 shortened < coenzyme factor (compare quot. 1937) < co-enzyme n. + factor n.Previous versions of the OED give the stress as: co-ˈfactor. Thesaurus » Categories » 1. Algebra. One of the several factors of a product; a coefficient. 2. Chemistry. (a) Any substance other than the substrate (as a co-enzyme or a metal ion) the presence of which is necessary for the activity of a particular enzyme; (b) (see quot. 1956); (formerly called co-enzyme factor). ΚΠ 1937 Dewan & Green in Nature 25 Dec. 1098/1 A New Oxidation Catalyst... We have succeeded in resolving the so-called coenzyme oxidase into three insoluble components, (1) the coenzyme factor... The coenzyme factor catalyses the first oxidation.] 1945 Jrnl. Cellular & Compar. Physiol. 25 12 The virus T₄..is not effective in lysing such irradiated cells unless a co-factor such as tryptophane is present in the mixture to enhance its rate of adsorption on the host. 1949 Adv. in Enzymol. IX. 178 Certain ‘cofactors’, such as l-tryptophan, have the power of promoting adsorption of certain bacteriophages on their hosts. 1956 Blakiston's New Gould Med. Dict. (ed. 2) 265/2 Cofactor, in bacteriology, any amino acid which must be present in the medium to activate phage to adsorb host bacteria. 1958 M. Dixon & E. C. Webb Enzymes ix. 394 An additional substance besides the enzyme and substrate is required in many cases in order that the reaction may proceed. Such ‘cofactors’ are found unchanged at the end of the reaction and may therefore be regarded as an essential part of the catalytic mechanism. The majority of enzyme cofactors may be broadly divided into..(a) specific coenzymes..(b) activators. This entry has not yet been fully updated (first published 1989; most recently modified version published online June 2021). < n.1945
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