单词 | comedo |
释义 | comedon. A small plug of sebum and cellular debris, often darkly pigmented at its superficial end, which forms (typically in the skin disease acne vulgaris) in a hair follicle and can be extruded from the follicle by pressure; a follicle containing such a plug. Also: the condition of having such plugged follicles (now rare).Originally believed to be a maggot or small worm (see quot. 1730).An open comedo has a relatively wide opening onto the skin, typically filled with melanin-pigmented cellular debris; = blackhead n.2 2.A closed comedo has a narrow or obstructed opening and may rupture and induce inflammation in surrounding tissue; = whitehead n.1 5. ΘΚΠ the world > health and disease > ill health > a disease > eruption > [noun] > comedo comedo1730 worm1730 blackhead1837 whitehead1886 waster1899 1730 Dr. Allen's Synopsis Medicinæ II. xv. 220 Crinones or Comedones are small Worms under the Skin, disposing Infants to a Consumption; they most commonly seize the Musculous Parts. 1798 R. Hooper Compend. Med. Dict. Crinones, Comedones, collections of a sebaceous fluid in the cutaneous follicles upon the face and breast, which appear like black spots, and when pressed out, look like small worms, or, as they are commonly called, maggots. 1847 E. Wilson On Dis. Skin (ed. 2) 364 When the substance expressed from one of these comedones is examined with the microscope, it is found that the sebaceous mass of which it is composed is altered in its composition. 1877 W. T. Fox Atlas Skin Dis. 98 But Acne Simplex is nothing more nor less than inflamed comedo. 1915 Jrnl. Cutaneous Dis. 33 66 The affected area contained comedos and acne-like lesions. 1993 J. Meades Pompey (1994) 145 You don't know that his nose is maculate with mauve pores and grey comedos. 2004 Independent 2 Aug. (Review section) 9/5 Blackheads, also known as comedones, are small dark spots caused by plugs that block skin pores. Derivatives coˈmedonal adj. of, relating to, or of the nature of a comedo; formed from or characterized by the presence of comedones. ΚΠ 1896 N.Y. Med. Jrnl. 63 402/1 When the suppuration took place in this way the comedonal mantle was usually intact and completely closed the lower extremity. 1960 A.M.A. Arch. Dermatol. 81 458 (title) Polyporous comedonal cyst. 2012 Cape Argus (Nexis) 3 Oct. 20 Topical retinoids are effective in the treatment of comedonal acne due to their ability to normalise follicular hyperkeratosis. This entry has been updated (OED Third Edition, June 2017; most recently modified version published online June 2022). < n.1730 |
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