conformationn.

/kɒnfɔːˈmeɪʃən/

Etymology: < Latin conformātiōn-em, noun of action fromconformāre to conform: so in French (since 16th cent. in Littré).

a. The action of conforming or bringing into conformity (to); adjustment in form or character to some pattern or example; adaptation.The word may have been intended in the following quot.:

?1530 tr. J. Colet Serm. Conuocacion Paulis i. sig. Aivv I wull speke..of confirmation [1661 Conformation] ...Be you nat conformable to this worlde.

ΘΚΠ

the world > relative properties > order > agreement, harmony, or congruity > adaptation or adjustment > [noun] > in order to conform

conformation1534

accordment1783

assimilation1790

1534 J. Fewterer tr. U. Pinder Myrrour Christes Passion sig. Biii The relentynge shalbe to his perfecte conformation.

1660 R. Coke Justice Vindicated 6 Obedience..is the conformation of ones will to the rules & precepts of his superior.

a1676 M. Hale Primitive Originat. Mankind (1677) i. i. 9 They distort, stretch and reduce the Orders of things in a conformation to those pre-conceived Suppositions.

a1748 I. Watts Improvem. Mind in Wks. (1813) VIII. iv. 37 The conformation of our hearts and lives to the duties of true religion and morality.

b. History of Language. Form-assimilation under the influence of analogy.

ΚΠ

1869 F. A. March Compar. Gram. Anglo-Saxon Lang. 83 Plural first person -m changes to -ð (conformation with 2d and 3d persons).

2. The symmetrical formation or fashioning of a thing in all its parts; putting into form.

ΘΚΠ

the world > space > shape > [noun] > shaping > putting into form

conformation1615

1615 H. Crooke Μικροκοσμογραϕια 268 Male children..haue their conformation the thirtieth day.

1681 Table of Hard Words in S. Pordage tr. T. Willis Remaining Med. Wks. Conformation, the framing, fashioning, or disposition of a thing.

1857–8 E. H. Sears Athanasia xi. 93 Ever and everywhere body is the creation of life, and is the conformation of its instincts and affections.

a. The manner in which a thing is formed with respect to the disposition of its parts; form depending upon arrangement of parts; structure, organization.‘In Anatomy it is taken for the Figure or Disposition of the Parts of a Humane Body; and by some Writers in the Art of Physick, for an Essential Property of Health or Sicknesse’ ( Phillips 1706).

ΘΚΠ

the world > space > shape > [noun] > resulting from arrangement

order1578

shape1633

configuration1646

conformation1646

the world > relative properties > wholeness > mutual relation of parts to whole > [noun]

shapec1050

composition1382

temperc1400

confectionc1420

temperament1471

frame?1520

compage1550

architecture1590

compacture1590

structure?1591

fabricaturec1600

constitution1601

membrature1606

composture1614

compositure1625

contexturea1639

composure1639

economy1644

fabric1644

conformation1646

composier1648

constructurea1652

compages1660

mechanism1662

compound1671

construction1707

componency1750

formation1774

make-up1821

1646 Sir T. Browne Pseudodoxia Epidemica iii. xvii. 151 Many wayes of Coition, according to divers shapes and different conformations .

1694 J. Locke Ess. Humane Understanding (new ed.) ii. xxvii. 190 A rational Spirit..united to a Body of a certain conformation of Parts.

1695 J. Woodward Ess. Nat. Hist. Earth 142 Where there happens to be such a Structure and Conformation of the interiour Parts of the Earth.

1732 J. Arbuthnot Pract. Rules of Diet iii. 332 A bad Conformation of the Lungs and Thorax commonly attended with an Asthma.

1791 E. Burke Let. to Member National Assembly 59 Government wants..amendment in its conformation.

1869 C. Boutell tr. J. P. Lacombe Arms & Armour ix. 179 This conformation of the blade has the advantage of placing the centre of gravity in the hilt.

1872 J. Morley Voltaire i. 1 The mind and spiritual conformation of the West.

b. Chemistry and Biochemistry. Each of the different three-dimensional structures that may be adopted by a particular molecule and can interconvert freely, esp. by rotations about single bonds; the three-dimensional secondary and tertiary structure of a protein.

ΘΚΠ

the world > matter > chemistry > chemical structure or stereochemistry > [noun] > conformation

conformation1929

the world > life > biology > substance > proteins > [noun] > processes, parts, or structures

conformation1929

glycosylation1945

superstructure1952

register1956

resilin1960

1929 W. N. Haworth Constit. Sugars x. 92 The conformation of groups as distinct from structure or configuration.

1950 Experientia VI. 316/1 The word conformation is used to denote different strainless arrangements in space of a set of bonded atoms.

1956 L. F. Fieser & M. Fieser Org. Chem. (ed. 3) xii. 304 Conformation frequently influences reaction rate.

1964 A. White et al. Princ. Biochem. (ed. 3) ix. 156 ‘Conformation’ is used in protein chemistry to designate the over-all structure of a molecule in which asymmetry may be produced by a spiral arrangement (helix) or other special folding.

1970 A. L. Lehninger Biochemistry i. 28 A protein has only one specific three-dimensional conformation under normal intracellular conditions, called the native conformation, which is indispensable for its biological activity.

1974 Encycl. Brit. Macropædia IV. 1090/1 In the chair conformation, two geometrically distinct types of carbon-hydrogen bond are present.

1980 M. Orchin et al. Vocab. Org. Chem. v. 148 Unless it is held rigid by small rings or double bonds, a molecule can have an infinite number of conformations, but only one configuration.

This entry has not yet been fully updated (first published 1891; most recently modified version published online June 2020).

单词	conformation
释义	conformationn. /kɒnfɔːˈmeɪʃən/ Etymology: < Latin conformātiōn-em, noun of action fromconformāre to conform: so in French (since 16th cent. in Littré). 1. a. The action of conforming or bringing into conformity (to); adjustment in form or character to some pattern or example; adaptation.The word may have been intended in the following quot.: ?1530 tr. J. Colet Serm. Conuocacion Paulis i. sig. Aivv I wull speke..of confirmation [1661 Conformation] ...Be you nat conformable to this worlde. ΘΚΠ the world > relative properties > order > agreement, harmony, or congruity > adaptation or adjustment > [noun] > in order to conform conformation1534 accordment1783 assimilation1790 1534 J. Fewterer tr. U. Pinder Myrrour Christes Passion sig. Biii The relentynge shalbe to his perfecte conformation. 1660 R. Coke Justice Vindicated 6 Obedience..is the conformation of ones will to the rules & precepts of his superior. a1676 M. Hale Primitive Originat. Mankind (1677) i. i. 9 They distort, stretch and reduce the Orders of things in a conformation to those pre-conceived Suppositions. a1748 I. Watts Improvem. Mind in Wks. (1813) VIII. iv. 37 The conformation of our hearts and lives to the duties of true religion and morality. b. History of Language. Form-assimilation under the influence of analogy. ΚΠ 1869 F. A. March Compar. Gram. Anglo-Saxon Lang. 83 Plural first person -m changes to -ð (conformation with 2d and 3d persons). 2. The symmetrical formation or fashioning of a thing in all its parts; putting into form. ΘΚΠ the world > space > shape > [noun] > shaping > putting into form conformation1615 1615 H. Crooke Μικροκοσμογραϕια 268 Male children..haue their conformation the thirtieth day. 1681 Table of Hard Words in S. Pordage tr. T. Willis Remaining Med. Wks. Conformation, the framing, fashioning, or disposition of a thing. 1857–8 E. H. Sears Athanasia xi. 93 Ever and everywhere body is the creation of life, and is the conformation of its instincts and affections. 3. a. The manner in which a thing is formed with respect to the disposition of its parts; form depending upon arrangement of parts; structure, organization.‘In Anatomy it is taken for the Figure or Disposition of the Parts of a Humane Body; and by some Writers in the Art of Physick, for an Essential Property of Health or Sicknesse’ ( Phillips 1706). ΘΚΠ the world > space > shape > [noun] > resulting from arrangement order1578 shape1633 configuration1646 conformation1646 the world > relative properties > wholeness > mutual relation of parts to whole > [noun] shapec1050 composition1382 temperc1400 confectionc1420 temperament1471 frame?1520 compage1550 architecture1590 compacture1590 structure?1591 fabricaturec1600 constitution1601 membrature1606 composture1614 compositure1625 contexturea1639 composure1639 economy1644 fabric1644 conformation1646 composier1648 constructurea1652 compages1660 mechanism1662 compound1671 construction1707 componency1750 formation1774 make-up1821 1646 Sir T. Browne Pseudodoxia Epidemica iii. xvii. 151 Many wayes of Coition, according to divers shapes and different conformations . View more context for this quotation 1694 J. Locke Ess. Humane Understanding (new ed.) ii. xxvii. 190 A rational Spirit..united to a Body of a certain conformation of Parts. 1695 J. Woodward Ess. Nat. Hist. Earth 142 Where there happens to be such a Structure and Conformation of the interiour Parts of the Earth. 1732 J. Arbuthnot Pract. Rules of Diet iii. 332 A bad Conformation of the Lungs and Thorax commonly attended with an Asthma. 1791 E. Burke Let. to Member National Assembly 59 Government wants..amendment in its conformation. 1869 C. Boutell tr. J. P. Lacombe Arms & Armour ix. 179 This conformation of the blade has the advantage of placing the centre of gravity in the hilt. 1872 J. Morley Voltaire i. 1 The mind and spiritual conformation of the West. b. Chemistry and Biochemistry. Each of the different three-dimensional structures that may be adopted by a particular molecule and can interconvert freely, esp. by rotations about single bonds; the three-dimensional secondary and tertiary structure of a protein. ΘΚΠ the world > matter > chemistry > chemical structure or stereochemistry > [noun] > conformation conformation1929 the world > life > biology > substance > proteins > [noun] > processes, parts, or structures conformation1929 glycosylation1945 superstructure1952 register1956 resilin1960 1929 W. N. Haworth Constit. Sugars x. 92 The conformation of groups as distinct from structure or configuration. 1950 Experientia VI. 316/1 The word conformation is used to denote different strainless arrangements in space of a set of bonded atoms. 1956 L. F. Fieser & M. Fieser Org. Chem. (ed. 3) xii. 304 Conformation frequently influences reaction rate. 1964 A. White et al. Princ. Biochem. (ed. 3) ix. 156 ‘Conformation’ is used in protein chemistry to designate the over-all structure of a molecule in which asymmetry may be produced by a spiral arrangement (helix) or other special folding. 1970 A. L. Lehninger Biochemistry i. 28 A protein has only one specific three-dimensional conformation under normal intracellular conditions, called the native conformation, which is indispensable for its biological activity. 1974 Encycl. Brit. Macropædia IV. 1090/1 In the chair conformation, two geometrically distinct types of carbon-hydrogen bond are present. 1980 M. Orchin et al. Vocab. Org. Chem. v. 148 Unless it is held rigid by small rings or double bonds, a molecule can have an infinite number of conformations, but only one configuration. This entry has not yet been fully updated (first published 1891; most recently modified version published online June 2020). < n.1534
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