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单词 corticotrophic
释义

corticotrophicadj.

/ˌkɔːtɪkəʊˈtrɒfɪk//ˌkɔːtɪkəʊˈtrɒpɪk/
Forms: Also corticotropic.
Etymology: < cortico- comb. form + trophic adj.
Biochemistry.
= adrenocorticotropic adj.
ΚΠ
1934 Chem. Abstr. 28 6813/1 (heading) Comparison of the effects of the corticotropic hormone of the pituitary upon various animal species.
1935 Chem. Abstr. 29 5163/1 Animal charcoal absorbs the pigmentation hormone without affecting the corticotropic hormone.
1936 H. D. Rolleston Endocrine Organs iii. 64 Corticotropic..or Adreno-cortical Stimulating Hormone.
1939 Jrnl. Endocrinology 1 57 The growth response of hereditarily dwarfed mice and of pigeons to..corticotropic extracts and to thyroxin does not disprove the existence of growth hormone.
1944 Lancet 5 Feb. 188/2 The evidence for corticotrophic activity in anterior pituitary extracts is well established.

Derivatives

ˌcorticoˈtropin n. (also ˌcortico'trophin) [-in suffix1] = adrenocorticotropin n.
ΚΠ
1942 Jrnl. Endocrinology 3 8 These experiments strongly suggest the presence of two different factors in pituitary corticotrophin—one affecting adrenal weight, the other the distribution of lipoid in the cortex.
1943 Science 3 Sept. 225/1 It is generally believed that hypophyseal corticotropin is protein in nature.
1944 Lancet 5 Feb. 188/2 Thus corticotrophin has been postulated as being responsible for all or part of the growth-promoting activity, glycotropic activity and diabetogenic activity of anterior pituitary extracts, and..there is evidence to support all these claims, though not evidence enough to make them by any means cast-iron.
1952 Chem. Abstr. 46 6754 (heading) Treatment of ulcerative colitis with corticotropin (ACTH) and cortisone.
1962 Lancet 8 Dec. 1190/2 Patients with rheumatoid arthritis from ten British centres who had been treated with corticotrophin or steroids.
This entry has not yet been fully updated (first published 1972; most recently modified version published online March 2021).
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adj.1934
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