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单词 aldol condensation
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aldol condensation
aldol condensation n. [after German Aldolcondensation (1885 in the passage translated in quot. 1886; now Aldolkondensation)] a reaction between two aldehyde or two ketone molecules (or an aldehyde and a ketone) to yield a single molecule with one hydroxyl and one carbonyl group (exemplified by the conversion of acetaldehyde to aldol), this product typically losing a water molecule readily to form an unsaturated aldehyde or ketone.
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hydrolysis1880
aldol condensation1886
aldol reaction1888
aldolization1898
base exchange1912
acidolysis1930
1886 E. F. Smith tr. V. von Richter Chem. Carbon Compounds 152 The aldehydes condense readily, i.e., two molecules unite by means of two carbon atoms and water may or may not separate (aldehyde and aldol condensation [Ger. Aldehyd- und Aldolcondensation]).
1968 A. White et al. Princ. Biochem. (ed. 4) xviii. 397 This enzyme can catalyze an aldol condensation between dihydroxyacetone phosphate and a wide variety of aldehydes.
2006 J. M. Hornback Org. Chem. (Internat. Student ed.) xx. 896 The Michael reaction in combination with an aldol condensation provides a useful method for the construction of six-membered rings.
extracted from aldoln.
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