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单词 cytokeratin
释义

> as lemmas

cytokeratin
cytokeratin n.
Brit. /ˌsʌɪtə(ʊ)ˈkɛrətɪn/
,
U.S. /ˌsaɪdoʊˈkɛrətn/
Biochemistry any of a group of fibrous proteins which form intermediate-sized cytoskeletal filaments in epithelial cells.
ΚΠ
1978 W. W. Franke et al. in Exper. Cell Res. 116 443/2 On the basis of the similarity we suggest that 6–11 nm thick filaments present in a variety of epithelial cells contain prekeratin-like polypeptides for which we propose the collective term ‘cytokeratins’.
1989 N.Y. Times 21 Nov. c6/4 These [abnormal bone marrow] cells do not absorb bone marrow stains and stain positive for cytokeratin, a protein normally found in the lining of the breast and colon.
2002 Proc. National Acad. Sci. U.S.A. 99 2246/1 Disseminated cancer cells in bone marrow express epithelial cytokeratins (CK) and are therefore immunocytochemically detectable.
extracted from cyto-comb. form
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as lemmas
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