α. 1900s– cytomegalia.
β. 1900s– cytomegaly.
cytomegalyn.
/ˌsʌɪtə(ʊ)ˈmɛɡəli/, /ˌsʌɪtə(ʊ)ˈmɛɡl̩i/, U.S. /ˌsaɪdəˈmɛɡəli/ Medicine and Pathology.
Abnormal enlargement of cells, seen in cytomegalovirus and certain other viral infections and in various other diseases and disorders; an instance of this. Also (esp. in early use): a disease characterized by cytomegaly, spec. cytomegalovirus infection. Cf. megalocytosis n.
ΚΠ
1921 E. W. Goodpasture & F. B. Talbot in Amer. Jrnl. Dis. Children 21 425 It seems advisable to identify the condition with a descriptive name, and we would suggest that it be called cytomegalia to emphasize the notable enlargement of the cells affected, and at the same time to distinguish it from those forms of cellular enlargement which at present are included under the general term giant cells.
1947 Jrnl. Pathol. & Bacteriol. 59 392 Of all the lesions associated with inclusion bodies the only ones which show cytomegaly, intranuclear and cytoplasmic changes identical with those in the organs of infants are the salivary-gland virus diseases of rodents and monkeys.
1979 Jrnl. Clin. Pathol. 32 306/1 A theory that adrenal cytomegaly may be an indication of polyploidy occurring when the adrenal cortical cells are intensely stimulated was proposed.
1993 Toxicol. Lett. 68 203 Dichloroacetate induces a markedly enlarged liver associated with a cytomegaly and large accumulations of glycogen.
2004 R. J. Goldstein Betta Handbk. vi. 102/1 Strawberry-like lumps on the body and (mostly) the fins consist of cells enlarged many times their normal diameter (cytomegaly) because of the [lymphocystis] viruses inside.
This is a new entry (OED Third Edition, November 2010; most recently modified version published online March 2022).
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n.1921