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单词 cytosol
释义

cytosoln.

Brit. /ˈsʌɪtə(ʊ)sɒl/, U.S. /ˈsaɪdəˌsɔl/, /ˈsaɪdəˌsɑl/
Origin: Formed within English, by compounding. Etymons: cyto- comb. form, sol n.6
Etymology: < cyto- comb. form + sol n.6 Compare earlier organosol n., plasmasol n., etc.
Cell Biology.
The fluid component or phase of cytoplasm, as opposed to its organelles, endoplasmic reticulum, and other organized structures.
ΘΚΠ
the world > life > biology > substance > cell > cell substance > [noun] > protoplasm or cytoplasm > structure or substance in cytoplasm
microsome1881
myoneme1893
tonofibril1901
Holmgren1921
tonofibrilla1925
cytoskeleton1936
protofibril1948
protofilament1960
microfilament1963
tonofilament1964
cytosol1965
1965 H. A. Lardy in B. Chance et al. Control of Energy Metabolism 245 The term cytosol will be used to designate that portion of the cell which is found in the supernatant fraction after centrifuging the homogenate at 105,000 × g for 1 hour. It refers specifically to the cytoplasm minus mitochondria and endoplasmic reticulum components.
1972 Science 7 July 56/1 Although long-chain fatty acids are at best poorly soluble in aqueous media, a mechanism to account for the apparent facility with which they traverse the cytosol (aqueous cytoplasm) has not been identified.
2007 D. Rutkowski & V. Lingappa in B. Lewin et al. Cells iii. 125 Translocated proteins can be exported to the cytosol, where they are ubiquitinated and degraded by the proteasome.

Derivatives

ˌcytoˈsolic adj. of or relating to the cytosol.
ΘΚΠ
the world > life > biology > substance > cell > cell substance > [adjective] > protoplasm or cytoplasm > of structure or substance in
cytoskeletal1937
cytosolic1969
microfilamentous1970
1969 Jrnl. Biol. Chem. 244 4359/1 The lack of cytosolic NADH in these livers is reflected in the decreased lactate to pyruvate ratio.
1982 T. M. Devlin Textbk. Biochem. xxi. 1020 The mitochondria are impermeable to cytosolic oxalacetate.
2003 Science 21 Nov. 1297/2 Proteins destined for insertion into or across a membrane carry a sequence, usually at the N terminus, that distinguishes them from soluble cytosolic proteins.
This entry has been updated (OED Third Edition, November 2010; most recently modified version published online March 2022).
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n.1965
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