单词 | cytosol |
释义 | cytosoln. Cell Biology. The fluid component or phase of cytoplasm, as opposed to its organelles, endoplasmic reticulum, and other organized structures. ΘΚΠ the world > life > biology > substance > cell > cell substance > [noun] > protoplasm or cytoplasm > structure or substance in cytoplasm microsome1881 myoneme1893 tonofibril1901 Holmgren1921 tonofibrilla1925 cytoskeleton1936 protofibril1948 protofilament1960 microfilament1963 tonofilament1964 cytosol1965 1965 H. A. Lardy in B. Chance et al. Control of Energy Metabolism 245 The term cytosol will be used to designate that portion of the cell which is found in the supernatant fraction after centrifuging the homogenate at 105,000 × g for 1 hour. It refers specifically to the cytoplasm minus mitochondria and endoplasmic reticulum components. 1972 Science 7 July 56/1 Although long-chain fatty acids are at best poorly soluble in aqueous media, a mechanism to account for the apparent facility with which they traverse the cytosol (aqueous cytoplasm) has not been identified. 2007 D. Rutkowski & V. Lingappa in B. Lewin et al. Cells iii. 125 Translocated proteins can be exported to the cytosol, where they are ubiquitinated and degraded by the proteasome. Derivatives ˌcytoˈsolic adj. of or relating to the cytosol. ΘΚΠ the world > life > biology > substance > cell > cell substance > [adjective] > protoplasm or cytoplasm > of structure or substance in cytoskeletal1937 cytosolic1969 microfilamentous1970 1969 Jrnl. Biol. Chem. 244 4359/1 The lack of cytosolic NADH in these livers is reflected in the decreased lactate to pyruvate ratio. 1982 T. M. Devlin Textbk. Biochem. xxi. 1020 The mitochondria are impermeable to cytosolic oxalacetate. 2003 Science 21 Nov. 1297/2 Proteins destined for insertion into or across a membrane carry a sequence, usually at the N terminus, that distinguishes them from soluble cytosolic proteins. This entry has been updated (OED Third Edition, November 2010; most recently modified version published online March 2022). < n.1965 |
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