cyclinn.

/ˈsʌɪklɪn/

Etymology: < cycle n.¹ or cycle v.¹ + -in suffix¹.

Biochemistry.

1. A protein found in cell nuclei, in amounts which fluctuate during the cell cycle, being greatest during DNA replication. Now called proliferating cell nuclear antigen (PCNA).

ΘΚΠ

the world > life > biology > substance > proteins > [noun]

casein1838

albuminoid1855

xanthoglobulin1868

myochrome1872

xanthoprotein1883

histone1885

globulose1886

phaseolin1893

leucosin1894

nucleohistone1894

nucleon1895

mucoid1898

protone1898

mucinoid1902

myohaemoglobin1906

nucleoprotamine1911

cytozyme1914

leaf protein1917

cytochrome1925

mucoprotein1925

myoglobin1925

flavoprotein1934

oxymyoglobin1935

ferritin1937

lipovitellin1942

arthropodin1947

trypticase1947

erythropoietin1948

phosvitin1948

opsin1951

orosomucoid1955

metallothionein1960

plastocyanin1961

aequorin1962

ferredoxin1962

LDL1962

fetoprotein1964

thioredoxin1964

actinin1965

adrenodoxin1965

lactoferrin1965

myoglobulin1965

rubredoxin1965

uniporter1967

miraculin1968

nexin1970

bacteriorhodopsin1971

molybdoprotein1971

monellin1972

cytokine1974

ankyrin1975

clathrin1975

electromorph1975

tau1975

uniport1975

microtrabecula1976

porin1976

osteocalcin1977

calmodulin1978

monokine1978

PCNA1978

vimentin1978

interleukin1979

laminin1979

titin1979

villin1979

cyclin1981

triskele1981

acumentin1982

perforin1983

statin1985

activin1986

addressin1988

synuclein1988

chemokine1992

1981 R. Bravo et al. in Exper. Cell Res. 136 319/1 To avoid confusion between the different numbering systems we have termed the nuclear acidic polypeptide ‘cyclin’.

1984 Nature 24 May 376/1 We suggest that the name PCNA be used in future, as it is the earlier nomenclature and the term cyclin has recently become ambiguous.

1989 Proc. National Acad. Sci. U.S.A. 86 3189/1 Proliferating-cell nuclear antigen (PCNA; also called cyclin) was originally described in proliferating mammalian cells as a nuclear protein.

2. Any of a class of structurally similar proteins that are synthesized and destroyed at different points in the cell cycle and are instrumental in the control of DNA replication and division in eukaryotes.

ΘΚΠ

the world > life > biology > substance > proteins > [noun] > cyclin

cyclin1983

1983 T. Evans et al. in Cell 33 389/1 Oocytes of the surf clam Spisula solidissima also contain proteins that only start to be made after fertilization and are destroyed at certain points in the cell division cycle. We propose to call these proteins the cyclins.

1985 Biol. Bull. 169 545 The Cyclin A protein which is encoded by a maternally stored mRNA was also studied.

1986 Cell 47 870/1 What is the relationship between cyclin A and cyclin B, a related but distinctly different protein whose levels also oscillate in phase with the mitotic cell cycle?

1991 EMBO Jrnl. 9 2865/2 Cyclin B has been isolated from a wide variety of organisms that include yeast, sea urchin, starfish, clam, frog, fly and man.

1992 Trends Cell Biol. II. 77/1 Cyclins have come to occupy a central position in our understanding of the regulatory processes that coordinate the cell cycle.

This entry has not yet been fully updated (first published 1997; most recently modified version published online June 2018).

单词	cyclin
释义	cyclinn. /ˈsʌɪklɪn/ Etymology: < cycle n.¹ or cycle v.¹ + -in suffix¹. Biochemistry. 1. A protein found in cell nuclei, in amounts which fluctuate during the cell cycle, being greatest during DNA replication. Now called proliferating cell nuclear antigen (PCNA). ΘΚΠ the world > life > biology > substance > proteins > [noun] casein1838 albuminoid1855 xanthoglobulin1868 myochrome1872 xanthoprotein1883 histone1885 globulose1886 phaseolin1893 leucosin1894 nucleohistone1894 nucleon1895 mucoid1898 protone1898 mucinoid1902 myohaemoglobin1906 nucleoprotamine1911 cytozyme1914 leaf protein1917 cytochrome1925 mucoprotein1925 myoglobin1925 flavoprotein1934 oxymyoglobin1935 ferritin1937 lipovitellin1942 arthropodin1947 trypticase1947 erythropoietin1948 phosvitin1948 opsin1951 orosomucoid1955 metallothionein1960 plastocyanin1961 aequorin1962 ferredoxin1962 LDL1962 fetoprotein1964 thioredoxin1964 actinin1965 adrenodoxin1965 lactoferrin1965 myoglobulin1965 rubredoxin1965 uniporter1967 miraculin1968 nexin1970 bacteriorhodopsin1971 molybdoprotein1971 monellin1972 cytokine1974 ankyrin1975 clathrin1975 electromorph1975 tau1975 uniport1975 microtrabecula1976 porin1976 osteocalcin1977 calmodulin1978 monokine1978 PCNA1978 vimentin1978 interleukin1979 laminin1979 titin1979 villin1979 cyclin1981 triskele1981 acumentin1982 perforin1983 statin1985 activin1986 addressin1988 synuclein1988 chemokine1992 1981 R. Bravo et al. in Exper. Cell Res. 136 319/1 To avoid confusion between the different numbering systems we have termed the nuclear acidic polypeptide ‘cyclin’. 1984 Nature 24 May 376/1 We suggest that the name PCNA be used in future, as it is the earlier nomenclature and the term cyclin has recently become ambiguous. 1989 Proc. National Acad. Sci. U.S.A. 86 3189/1 Proliferating-cell nuclear antigen (PCNA; also called cyclin) was originally described in proliferating mammalian cells as a nuclear protein. 2. Any of a class of structurally similar proteins that are synthesized and destroyed at different points in the cell cycle and are instrumental in the control of DNA replication and division in eukaryotes. ΘΚΠ the world > life > biology > substance > proteins > [noun] > cyclin cyclin1983 1983 T. Evans et al. in Cell 33 389/1 Oocytes of the surf clam Spisula solidissima also contain proteins that only start to be made after fertilization and are destroyed at certain points in the cell division cycle. We propose to call these proteins the cyclins. 1985 Biol. Bull. 169 545 The Cyclin A protein which is encoded by a maternally stored mRNA was also studied. 1986 Cell 47 870/1 What is the relationship between cyclin A and cyclin B, a related but distinctly different protein whose levels also oscillate in phase with the mitotic cell cycle? 1991 EMBO Jrnl. 9 2865/2 Cyclin B has been isolated from a wide variety of organisms that include yeast, sea urchin, starfish, clam, frog, fly and man. 1992 Trends Cell Biol. II. 77/1 Cyclins have come to occupy a central position in our understanding of the regulatory processes that coordinate the cell cycle. This entry has not yet been fully updated (first published 1997; most recently modified version published online June 2018). < n.1981
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