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单词 disease
释义

diseasen.

Brit. /dᵻˈziːz/, U.S. /dəˈziz/ (In sense 2)Brit. /dᵻˈziːz/, U.S. /dəˈziz/
Forms: Middle English decas, Middle English deces, Middle English deisese, Middle English desaise, Middle English deseas, Middle English deseisse, Middle English deses, Middle English desese, Middle English desesse, Middle English deseyce, Middle English deseysse, Middle English dicese, Middle English diseasse, Middle English disees, Middle English diseese, Middle English disese, Middle English disess, Middle English dishese, Middle English dissease, Middle English disseease, Middle English disseese (in a late copy), Middle English disses, Middle English dissese, Middle English dysase, Middle English dyses, Middle English dysese, Middle English dysesse, Middle English dyseze, Middle English dyshes, Middle English dyshese, Middle English dyssaise, Middle English dyssese, Middle English dyssesse, Middle English dyszese, Middle English–1500s dysease, 1500s–Middle English dyseasse, Middle English–1500s dyssease, Middle English– disease, 1500s desease, 1500s desees, 1500s dessays, 1500s disseyse, 1500s dysseasse, 1600s– dis-ease; Scottish pre-1700 deceas, pre-1700 deceise, pre-1700 deseas, pre-1700 deseese, pre-1700 deseis, pre-1700 deses, pre-1700 deseys, pre-1700 disais, pre-1700 disase, pre-1700 disays, pre-1700 disceis, pre-1700 diseais, pre-1700 diseis, pre-1700 dises, pre-1700 disese, pre-1700 diseys, pre-1700 dissese, pre-1700 dyses, pre-1700 dysese, pre-1700 dyseys, pre-1700 dysses, pre-1700 1700s– disease. N.E.D. (1896) also records a form late Middle English dyseysse.
Origin: A borrowing from French. Etymons: French disease, desaise.
Etymology: < Anglo-Norman disease, desease, disese, etc., Anglo-Norman and Middle French desaise inconvenience, hardship (end of the 13th cent. in Old French), distress, grief (early 14th cent.), sickness (late 14th cent. or earlier), trouble, misfortune (end of the 14th cent. or earlier), discomfort, displeasure, impediment (all a1412) < des- dis- prefix + aise ease n. Compare earlier misease n.1Compare Old Occitan desaize, desaize sickness, deprivation, suffering (12th cent.).
1.
a. Harm, injury, wrong; (also) an instance of this. Obsolete. to do disease to: to harm, to injure; = disease v. 2a.
ΘΚΠ
the world > action or operation > harm or detriment > harm, injury, or wrong > [noun]
loathc900
harmOE
teenOE
griefc1330
injurec1374
injuryc1384
truitc1390
spitea1400
wrethec1400
supprise1442
trouble1463
damage1470
objectionc1475
interess1489
tort1532
mishanter1754
the world > action or operation > harm or detriment > harm, injury, or wrong > harm, injure, or commit offence against [verb (transitive)]
misdoc1230
forworkc1275
wrongc1330
to do (one) spite or a spitec1380
to commit (also do, make) an offencec1384
offenda1387
unrighta1393
to do disease toc1400
injuryc1484
offence1512
misfease1571
watcha1586
injure1597
envya1625
disserve1637
hinder1639
disservice1837
serve1887
c1384 Bible (Wycliffite, E.V.) (Douce 369(2)) (1850) Dan. vi. 2 That..the kyng shulde not suffre eny disese [L. molestiam].
1387–8 Petition London Mercers in R. W. Chambers & M. Daunt Bk. London Eng. (1931) 37 (MED) For oon the grettest remedye..forto ayein-stonde many of thilke diseses..we prayen..that the statut ordeigned and made bi parlement holden at westmystre in the sexte yere of owre Kyng..mowe..be execut.
1414 Petition in Rotuli Parl. (1767–77) IV. 58/1 To have remedie and socour of the grete wronges, mischiefs, and diseses, the whiche we have suffred these x zer.
?a1425 Mandeville's Trav. (Egerton) (1889) 98 Nedders and oþer venymous bestez of þat cuntree duse na diseese to na straungers ne pilgrimes.
a1500 (?a1450) Gesta Romanorum (BL Add. 9066) (1879) 309 The Emperour comaunded, that no man shuld dispoile the ymages..ne to hem do no disease.
b. Hardship, suffering; pain, misery, misfortune; an instance of this. Obsolete.
Π
?a1400 (a1338) R. Mannyng Chron. (Petyt) (1996) ii. l. 4110 Go & mak his pes or he do þe more stoure, & þou to þi deses may haf þe frute & floure.
c1405 (c1395) G. Chaucer Canon's Yeoman's Tale (Ellesmere) (1875) l. 747 Vn-to shrewes ioye it is and ese To haue hir felawes in peyne and disese.
c1450 (?c1400) Three Kings Cologne (Cambr. Ee.4.32) (1886) 26 (MED) Ihesu crist..was bore of oure lady..withoute any dissese or sorwe of her body.
?c1450 Life St. Cuthbert (1891) l. 151 Sho sufferd calde, sho sufferd hete, So sho was to dyses vsed, Þat no trauayle sho refused.
a1500 in Antiquary (1901) 37 54 (MED) Put in a tonne full of fervent brennynge oyle..she..abode therin withoute any Disease, joiyng her there.
1696 T. Rogers Happiness of Quiet Mind 57 When St. Paul had a Thorn in the Flesh, a painful Disease, that created as much trouble to him, as a Thorn usually does in the tender Flesh; He sought the Lord thrice.
2.
a. Now chiefly in form dis-ease. Absence of ease; uneasiness, discomfort; disquiet, disturbance; trouble. Formerly also: †inconvenience, annoyance (obsolete).Apparently falling out of use after the early 17th cent. and re-coined in the late 19th cent., probably as a separate formation directly from dis- prefix and ease n.
ΘΚΠ
the mind > emotion > suffering > state of being upset or perturbed > [noun]
stirringc888
maleasea1300
uneasea1300
diseasec1330
perturbationa1382
unrestfulnessc1384
disturbancea1387
unroc1390
distroublancea1400
perturbancec1425
unquietnessc1460
inquietation1461
conturbationc1470
unheart's-ease1470
distroubling1487
wanease15..
inquietness?1504
unrufe1508
sturt1513
pertroublancea1522
inquieting1527
unquieting1548
turmoiling1550
unquiet1551
agitation?1555
storm1569
wanrest1570
discountenance1577
float1579
disquiet1581
brangling1584
diseasefulnessa1586
restlessness1597
hurry1600
disturbancy1603
disquietment1606
disordera1616
laruma1616
uneasinessa1616
diseasementa1617
discomposture1622
discomposition1624
whirr1628
discomposednessa1631
discomposure1632
pother1638
incomposedness1653
inquietude1658
uneasefulness1661
toss1666
disquietednessa1680
intranquillitya1699
disquietude1709
bosom-broil1742
discomfort1779
rufflement1806
feeze1825
uncomfortableness1828
discomforture1832
astasia1839
dysphoria1842
purr1842
peacelessness1852
palaver1899
perturbment1901
heebie-jeebies1923
wahala1966
agita1979
a1387 J. Trevisa tr. R. Higden Polychron. (St. John's Cambr.) (1871) III. 287 Þe disese of þouȝt mowe be putte away.
a1400 (?c1300) Bevis of Hampton (Egerton) l. 1418 Disseise [c1330 Auch. Þow schelt haue meche miseise..til þow be ded, Boute ech a dai quarter of a lof bred].
c1430 N. Love Mirror Blessed Life (Brasenose e.9) (1908) 143 His disciples weren in the see in grete disese.
a1500 (?c1450) Merlin iii. 54 Thei shull haue grete dissese for lakke of water.
a1547 Earl of Surrey Poems (1964) 16 Till thou know my hole disseyse my hart can have no rest.
?1615 G. Chapman tr. Homer Odysses (new ed.) iv. 1088 Doth sleep thus seize Thy powers, affected with so much dis-ease?
1623 W. Lisle in tr. Ælfric Saxon Treat. Old & New Test. Ded. xxiii Some grudge of old disease, Which will enforce us fortifie our townes.
1895 H. W. Dresser Power of Silence i. 14 Can we not become adjusted to the situation as it actually is, and stop this continual rebellion, this sense of dis-ease and lack of harmony with the inevitable?
1935 W. H. Auden & C. Isherwood Dog beneath Skin iii, in Eng. Auden (1986) 114 When he to ease His heart's disease Must cross in sorrow Corrosive seas As dolphin go.
1960 Encounter Mar. 78/1 The fear and dis-ease which underlie the more obvious nostalgia.
2020 Jerusalem Post (Nexis) 13 Nov. (Features section) 35 We each may feel or show a sense of dis-ease in differing ways. Talk to your children and help them put a name on their feelings so that they can better understand them.
b. A cause of uneasiness, discomfort, or disquiet; a trouble, an annoyance, a grievance. Obsolete (rare and regional in later use).
ΘΚΠ
the mind > emotion > suffering > state of annoyance or vexation > [noun] > cause of annoyance or vexation
thornc1230
dreicha1275
painc1375
cumbrance1377
diseasec1386
a hair in one's necka1450
molestationc1460
incommodity?a1475
melancholya1475
ensoigne1477
annoyance1502
traik1513
incommode1518
corsie1548
eyesore1548
fashery1558
cross1573
spite1577
corrosive1578
wasp1588
cumber1589
infliction1590
gall1591
distaste1602
plague1604
rub1642
disaccommodation1645
disgust1654
annoyment1659
bogle1663
rubber1699
noyancea1715
chagrins1716
ruffle1718
fasha1796
nuisance1814
vex1815
drag1857
bugbear1880
nark1918
pain in the neck (also arse, bum, etc.)1933
sod1940
chizz1953
c1405 (c1390) G. Chaucer Nun's Priest's Tale (Ellesmere) (1872) Prol. l. 3961 It is a greet disese Where as men han been in greet welthe and ese To heeren of hire sodeyn fal.
?1443 M. Paston in Paston Lett. & Papers (2004) I. 218 Sende me a letter as hastely as ȝe may, yf wrytyn be non dysesse to yow.
a1667 Bp. J. Taylor Serm. xxv. §5, in Wks. (1850) IV. 641 The disemployed is a disease, and like a long sleepless night to himself, and a load to his country.
1712 H. Prideaux Direct. Church-wardens (ed. 4) 59 [It] is only for their own ease, and that must not be made a dis-ease to the rest of the Parish.
1888 F. T. Elworthy W. Somerset Word-bk. (at cited word) I hope I shan't be no disease to ee.
3.
a. Sickness (in a person, animal, or plant); disturbance or impairment of the function (and often also the structure) of the body, a part of the body, or the mind. In later use frequently with modifying word, indicating the site, nature, cause, etc., of sickness.
ΘΚΠ
the world > health and disease > ill health > [noun]
unhealc700
untrumnessc897
adleeOE
sicknessc967
cothec1000
unhealthc1000
woe?a1200
ail?c1225
lying?c1225
maladyc1275
unsoundc1275
feebless1297
languora1375
languishc1384
disease1393
aegritudea1400
lamea1400
maleasea1400
soughta1400
wilc1400
malefaction?a1425
firmityc1426
unwholesomenessc1449
ill1450
languenta1500
distemperancea1535
the valley of the shadow of death1535
affect?1537
affection?1541
distemperature1541
inability1547
sickliness1565
languishment1576
cause1578
unhealthfulness1589
crazedness1593
languorment1593
evilness1599
strickenness1599
craziness1602
distemper1604
unsoundness1605
invaletude1623
unhealthiness1634
achaque1647
unwellness1653
disailment1657
insalubrity1668
faintiness1683
queerness1687
invalidity1690
illness1692
ill health1698
ailment1708
illing1719
invalescence1724
peakingness1727
sickishness1727
valetudinariness1742
ailingness1776
brash1786
invalidism1794
poorliness1814
diseasement1826
invalidship1830
valetudinarianism1839
ailing1862
invalidhood1863
megrims1870
pourriture1890
immersement1903
bug1918
condition1920
a1393 J. Gower Confessio Amantis (Fairf.) vi. l. 1016 He was full of such desese, That he mai noght the deth eschape.
c1450 (?a1400) Wars Alexander (Ashm.) l. 2549 He was fallen in a feuire... Þai..said ilkane to othire: ‘Be þis disese to ser Darie & his dukis knawen, He sall vs..surely en[c]ounbre.’
1661 R. Lovell Πανζωορυκτολογια, sive Panzoologicomineralogia 417 The strabisme, or squintness, caused by evil conformation, custome, or disease.
1744 J. Thomson Summer in Seasons (new ed.) 97 The dire Power of pestilent Disease.
1788 E. Gibbon Decline & Fall (1846) V. l. 10 The legions of Augustus melted away in disease and lassitude.
1834 J. Hayward Inq. Causes Fruitfulness & Barrenness Plants & Trees vi. 150 The indications of disease in plants are as perceptible and evident to the eye of a careful observer, as those of animals.
1852 Guy's Hosp. Rep. 2nd Ser. 8 289 We shall find that the occurrence of kidney disease alone is far less frequent than that of heart or liver disease alone.
1879 ‘E. Garrett’ House by Wks. II. 42 Suppressing disease instead of curing it.
1908 J. G. Adami Princ. Pathol. I. i. 20 If health be regarded as the indication of perfect functional activity, and disease of imperfect function, the two merge imperceptibly one into the other.
1968 New Eng. Jrnl. Med. 11 Jan. 101/2 The patient presented the picture of the advanced stage of malignant disease.
2021 Los Angeles Times (Nexis) 19 July a1 Fully vaccinated people are extraordinarily protected from severe disease, hospitalization and death from COVID-19.
b. A sickness or instance of sickness (in a person, animal, or plant); a condition in which the function, and often also the structure, of the body or part of the body is disturbed or impaired; (also) a condition of disturbed or impaired mental function (now somewhat rare); esp. such a condition in which characteristic symptoms, typical physiological and anatomical changes, and (often) a specific causative agent or factor can be identified.Frequently with modifying word or words, indicating the nature, site, or cause of a disease, the name of the physician who first described it, etc. For more established formations of this type, see the first element.
ΘΚΠ
the world > health and disease > ill health > a disease > [noun]
soreOE
cothec1000
sicknessc1000
evilc1275
maladyc1275
grievance1377
passiona1382
infirmityc1384
mischiefa1387
affectiona1398
grievinga1398
grief1398
sicka1400
case?a1425
plaguec1425
diseasea1475
alteration1533
craze1534
uncome1538
impediment1542
affliction?1555
ailment1606
disaster1614
garget1615
morbus1630
ail1648
disaffect1683
disorder1690
illness1692
trouble1726
complaint1727
skookum1838
claim1898
itis1909
bug1918
wog1925
crud1932
bot1937
lurgy1947
Korean haemorrhagic fever1951
nadger1956
a1398 J. Trevisa tr. Bartholomaeus Anglicus De Proprietatibus Rerum (BL Add. 27944) (1975) I. vi. xxi. 328 He þat haþ þat disese oþir yuel þat hatte strangurya pissiþ ofte and litil.
?a1425 tr. Guy de Chauliac Grande Chirurgie (Hunterian) f. 72v (MED) Blodelesse of þe veyne þat is cleped Renalis oþer venalis, þe whiche is atwixe þe litel too and þe too nexte him, is good for cancrene, malum mortuum, and varices & for Sausfleume & for alle oþere melancolious passiouns oþer diseses of þe legges.
a1475 Bk. Quinte Essence (1889) 18 Oure quinte essence auri et perelarum heelith þese disesis.
1528 T. Paynell tr. Arnaldus de Villa Nova in Joannes de Mediolano Regimen Sanitatis Salerni sig. f That lettyng of blud shulde nat be moche vsed: for by oft vsyng thereof, one waxyng olde, falleth in to dyuers diseases, as epilencie, apoplexie, and palsey.
a1555 H. Latimer 27 Serm. (1562) ii. f. 140 It is an vnwholsome thing to bury within ye city,..the occasion of much sicknes & diseases.
1604 W. Shakespeare Hamlet iv. iii. 9 Diseases desperat growne, By desperat applyance are relieued. View more context for this quotation
1651 T. Hobbes Leviathan ii. xxix. 173 A Disease, which resembleth the Pleurisie.
1725 N. St. André in London Gaz. No. 6349/1 The..Woman had the Foul Disease.
1762 A. Dickson Treat. Agric. i. viii. 77 The diseases of plants we may possibly do something to prevent, but we can do little to remove.
1799 Med. & Physical Jrnl. 2 183 The diseases of human teeth and bones.
1836 Penny Cycl. VI. 93/2 Cabbages are subject to a peculiar disease..called clubbing.
1885 Law Times 79 161/2 The mare was suffering from no catching disease.
1912 Twin Falls (Idaho) Times 12 Oct. Is it not important that they also be taught how..to avoid the deferrable and preventable diseases which are now..destroying so many precious lives?
1963 Times 17 May 5/7 (advt.) Today the vet can control mortality from diseases like white scours.
2009 Sci. Amer. (U.K. ed.) Sept. 69/2 Among diseases of man and beast, anthrax stands as one of the oldest known and certainly one of the most storied.
c. figurative. A particular quality or disposition regarded as adversely affecting a person or group of people in a manner analogous to an illness.
ΘΚΠ
society > morality > moral evil > moral or spiritual degeneration > [noun] > corruption > a morbid moral condition
rusteOE
maladyc1385
disease1509
lepry1526
boil1537
leprosy?1555
imposthume1565
gangrene1588
ulcer1592
diseasedness1614
lesion1640
unwholesomeness1881
1517 S. Hawes Pastime of Pleasure (1928) xvi. 70 A a sayde counseyle, doubte ye neuer a dele But your dysease I shall by wysdome hele.
1609 S. Rowlands Famous Hist. Guy Earle of Warwick 57 Ambitious pride hath been my youths disease.
a1661 T. Fuller Hist. Worthies Eng. (1662) Warw. 124 Bad Latin was a catching disease in that age.
1785 B. Franklin Let. 28 Aug. in Trans. Amer. Philos. Soc. (1786) 2 20 The common causes of the smoking of chimneys..the principles on which both the disease and the remedy depend.
1844 R. W. Emerson New Eng. Reformers in Wks. (1906) I. 266 The disease with which the human mind now labours is want of faith.
1945 N.Y. Herald-Tribune 16 Dec. (Books) 3 ‘The French flu’ (Francophilia), a disease which ravages the mind.
2011 Church Times 15 July 29/1 The history of reading and of the book is very vulnerable to the academic disease of jargon-laden, self-referential introspection.
d. Deterioration or decomposition resulting from a biological, chemical, or physical process, affecting a product, substance, or object; an instance or type of this.Cf. earlier diseased adj. 1c.tin disease: see the first element.
Π
1733 P. Miller Gardeners Dict. (ed. 2) at Wine In those Diseases of Wine, wherein they become viscous and ropy.
1818 R. McWilliam Ess. on Dry Rot xv. 165 It is a custom there [sc. Genoa], as a preventive against the diseases of timber, to steep it about three years in fresh water immediately after it is felled.
1921 W. Jago & W. C. Jago Technol. Bread-making xvii. 345 During hot weather bread is liable to an outbreak of the disease called ‘rope’.
1986 J. C. T. Hollander & R. W. Lanting in T. Schneider Acidification & Policy Implications 243 There is much concern about a type of damage to reinforced concrete that is commonly referred to as concrete disease.
2009 J. H. Stubbs Time Honored vii. 101 Systematic operations like those now undertaken to clean and maintain the historic buildings of Paris help guard against unkempt appearance and future ‘stone disease’.

Compounds

C1. General use as a modifier, with the sense ‘of or relating to disease’.
Π
1855 A. Haviland Climate, Weather, & Dis. 39 It is the combination of conditions well blended together that gives an impulse to the disease-germ.
1883 Chem. News 24 Aug. 90/2 A mere citation of cases of disease-outbreak..would avail but little.
1938 S. M. Buchanan Doctr. Signatures iv. 97 Initial disturbance, complication, coction, crisis, and abscession..serve to mark the stages in disease histories even when they are not mentioned.
2021 N.Y. Times Mag. 28 Mar. 39/1 They might gain insights into the health or disease markers of entire population groups or countries.
C2. With participles, forming compounds in which disease expresses the object of the underlying verb, as in disease-causing, disease-producing, etc. Also similarly with agent nouns, as in disease-maker, etc.
ΚΠ
1649 T. Diconson in J. Bulwer Pathomyotomia sig. a2 Whence subtilely thou 'rt wont to ken & trace The Critciall [sic] Disease-discovering Face.
1865 E. B. Tylor Res. Early Hist. Mankind vi. 128 In the New Hebrides, there was a colony of disease-makers.
1886 Athenæum 7 Aug. 178/1 The coffee tree is the patient, the fungus..is the disease-causing agent.
1906 Westm. Gaz. 27 Aug. 5/1 The invasion of the body by disease-producing organisms.
1943 Life 20 Sept. 79/2 Running a close second to Anopheles as a disease-spreader is Aëdes aegypti.
2015 Atlantic Mar. 36/2 By inserting human genes into plants, scientists have been able to create disease-fighting proteins called ‘plantibodies,’ which work just like the antibodies that the human immune system makes.
C3.
disease-free n. not affected by disease or containing causative agents of disease; (also) free from recurrent disease, esp. malignant disease, after treatment.
ΘΠ
the world > health and disease > [adjective] > of health: good > free from disease
soundc1175
hailc1275
unfect?1504
unsick?1536
sicklessa1547
unafflicted1599
uninfected1625
diseaseless1653
hale1684
undiseased1745
unaffected1793
undisordereda1807
afflictionless1874
symptom-free1962
1876 Jrnl. Hort., Cottage Gardener, & Country Gentleman 23 Mar. 236/2 I require Potatoes for seed, and by taking-up every fourth row for this purpose I gain two important advantages—namely, space for the Celery, and a disease-free—aye, and almost disease-proof—stock of tubers.
1913 Misc. Papers (Circular U.S. Dept. Agric., Bureau Plant Industry, No. 126) 5 The yellow Bourbon cane which came from infected districts gave diseased shoots, while the same variety obtained from disease-free regions and grown adjacent to the former plants produced healthy shoots.
1977 Ann. Internal Med. 86 155/1 Advances in combination chemotherapy and in the ‘prophylaxis’ and therapy of meningeal leukemia have helped to prolong both survival and disease-free survival.
2018 P. Kimani Dance of Jakaranda iv. 72 As a dog's collar attests him to be disease-free through a raft of vaccinations, a kipande around a man's neck was his proof that he had been cleared by the colonial powers and did not pose a threat to his fellow man.
disease management n. (a) the treatment of disease; (b) (U.S.) a system that seeks to manage the chronic conditions of high-risk, high-cost patients as a group, aimed at improving the quality and reducing the cost of professional care, as well as encouraging patients to engage proactively in following a healthy lifestyle; frequently as a modifier, as in disease management program, disease management strategy, etc.
Π
1918 A. Caillé Postgraduate Med. p. v. The presentation here..embraces all modern methods of disease management of proven therapeutic value.
1974 Washington Post 15 Oct. a21/5 Most prominent surgeons do not limit their attack on disease to one narrowed area such as the breast... Telescopic approaches to disease management..has [sic] led to unfortunate conclusions.
1986 Ann. Rep. Rockefeller Found. 34 Health of Populations is creating a worldwide network in clinical epidemiology..using population-based research methods to identify the most cost-effective disease management strategies and health-care policies for their countries.
2004 Wall St. Jrnl. 9 Aug. (Central ed.) r5/2 The thinking behind disease management is that aggressive efforts to educate and monitor individuals with chronic illnesses—by means of frequent telephone calls from nurses, for instance—will make for healthier patients.
2015 C. P. McLaughlin & C. D. McLaughlin Health Policy Anal. (ed. 2) v. 123 The federal government..has encouraged state efforts to move more and more Medicaid recipients..into managed care programs and adopt disease management programs.
disease mongering n. depreciative (a) the action or practice of causing or spreading disease (obsolete); (b) the unnecessary or inappropriate labelling of a physical condition or behaviour as a disorder requiring medical treatment, typically considered to be done for the purpose of selling drugs or other treatments.In earliest use in the context of inoculation or vaccination being viewed with suspicion or hostility.
Π
1878 National Anti-compulsory-vaccination Reporter June 170/1 The..experiment of Dr. Reiss..who vaccinated..children from an ‘exquisitely scrofulous vaccinifer’, and saw scrofula develop itself in every one of them!.. The moral degradation of the modern medical school could scarcely be better exemplified... Away with its filthy disease-mongering.
1901 A. Westland Tocol. for Mothers iii. xvii. 207 All this playing with poxes or ‘disease mongering’ will be some day entirely done away with, and looked back upon with shame.
1992 Kirkus Rev. (Nexis) 1 Aug. Disease-mongering—convincing the healthy that they are sick or the slightly ill that they are very sick—is big business.
2011 N. M. Hadler Rethinking Aging v. 111 I have long pointed to osteoporosis as one of the best examples of disease mongering by the pharmaceutical industry... The thinning of our bones is a risk factor that has been turned into a horrifying disease.
disease-resistant n. and adj. (a) n. a (variety or breed of) plant or animal that has some ability to withstand disease or infection (somewhat rare); (b) adj. having some ability to withstand disease or infection.
ΚΠ
1880 Jrnl. Hort., Cottage Gardener, & Home Farmer 25 Mar. 231/2 Scotch Champion has recently come to the front [of potato varieties] with two strong recommendations—excellent quality and a disease-resistant.
1893 N. A. Cobb Plant Dis. & Remedies (New S. Wales Dept. Agric.) 18 Selection of disease-resistant sorts [of sugar-cane].
1926 Gleanings Bee Culture Mar. 189/1 He says to me to breed disease-resistants onto your winter-hunger resistants.
1946 E. Hoffmann & H. A. Johnson Successful Broiler Growing ii. 17 The demands of broiler growers in this area for a strong, disease resistant, rapidly growing, rapid feathering chick.
2013 S. Williams Creating Prairie Xeriscape (new ed.) vi. 92/2 ‘Golden Nugget’..is dense, dwarf, medium-dark green, has excellent wear tolerance and is disease resistant.
disease-ridden adj. affected by disease; harbouring disease or disease-causing agents.
ΘΠ
the world > health and disease > ill health > [adjective] > in state of ill health or diseased
untrumc825
sickc888
unwholec888
slackc897
unstronga900
sicklea1000
sam-halea1023
worseOE
attaint1303
languishinga1325
heallessc1374
sicklyc1374
sicklewa1387
bada1393
mishalea1400
languoring?c1425
distempered1440
unwell?c1450
detent?a1475
poora1475
languorousc1475
maladif1481
illa1500
maladiousc1500
wanthriven1508
attainted1509
unsound1513
acrazed1521
cracked1527
unsoundya1529
visited1537
infirmed1552
crazed1555
healthless1568
ill-liking1572
afflicted1574
crazy1576
unhealthful1580
sickish1581
valetudinary1581
not well1587
fainty1590
ill-disposed1596
unhealthsome1598
tainted1600
ill-affected1604
peaking1611
unhealthy1611
infirmited1616
disaffected1626
physical1633
illish1637
pimping1640
invalid1642
misaffected1645
valetudinarious1648
unhale1653
badly1654
unwholesome1655
valetudinous1655
morbulent1656
off the hooksa1658
mawkish1668
morbid1668
unthriven1680
unsane1690
ailing1716
not wellish1737
underlya1742
poorly1750
indifferent1753
comical1755
maladized1790
sober1808
sickened1815
broken-down1816
peaky1821
poorlyish1827
souffrante1827
run-down1831
sicklied1835
addle1844
shaky1844
mean1845
dauncy1846
stricken1846
peakyish1853
po'ly1860
pindling1861
rough1882
rocky1883
suffering1885
wabbit1895
icky-boo1920
like death warmed up1924
icky1938
ropy1945
crappy1956
hanging1971
sick as a parrot1982
shite1987
1857 J. C. Chambers Serm. preached at Perth & Other Parts Scotl. 1846–53 xlix. 433 It is this same forecasting—this same looking onward which sustains the widow and her fatherless children, the beggared merchant or tradesman.., the convicted criminal and the pain-worn, disease-ridden sufferer.
1923 F. J. Moberly Hist. Great War: Campaign in Mesopotamia I. 129 The total absence of any sanitary system or method and the presence of numerous disease-ridden brothels rendered both towns unsuitable for the billeting of troops.
2018 W. Davies Nerv. States (2019) iv. 98 A typical life has become longer and less disease-ridden.
This entry has been updated (OED Third Edition, December 2022).

diseasev.

Brit. /dᵻˈziːz/, U.S. /dəˈziz/
Forms: Middle English desese, Middle English deshese, Middle English desise, Middle English disase, Middle English diseasse, Middle English diseese, Middle English disesse, Middle English disseise, Middle English dissese, Middle English dysese, Middle English dyssese, Middle English–1500s desease, Middle English–1500s disese, Middle English–1500s dysease, Middle English– disease, 1500s desesse, 1600s discease; Scottish pre-1700 desase, pre-1700 desease, pre-1700 desese, pre-1700 dessese, pre-1700 discese, pre-1700 discess, pre-1700 diseis, pre-1700 dises, pre-1700 disese, pre-1700 dishes, pre-1700 dissase, pre-1700 dissese, pre-1700 dycess, pre-1700 dysese, pre-1700 dyssese, pre-1700 dyssess, pre-1700 1700s– disease. N.E.D. (1896) also records forms late Middle English dessayse, late Middle English dissease, late Middle English dysesse, late Middle English dyssesse.
Origin: Formed within English, by conversion. Etymon: disease n.
Etymology: < disease n. Compare misease v. and the French verb cited at that entry.Compare Old French desaaisier to deprive of ease (c1300; rare).
1.
a. transitive. To deprive (a person) of ease, make (a person) uneasy; to inflict discomfort or inconvenience upon; to trouble, to distress; to annoy, to vex. In early use also intransitive: to cause trouble or distress. Obsolete.
ΘΚΠ
the mind > emotion > suffering > state of being upset or perturbed > upset or perturb [verb (transitive)]
to-wendc893
mingeOE
dreveOE
angerc1175
sturb?c1225
worec1225
troublec1230
sturble1303
disturbc1305
movea1325
disturblec1330
drubblea1340
drovec1350
distroublec1369
tempestc1374
outsturba1382
unresta1382
stroublec1384
unquietc1384
conturb1393
mismaya1400
unquemea1400
uneasec1400
discomfita1425
smite?a1425
perturbc1425
pertrouble?1435
inquiet1486
toss1526
alter1529
disquiet1530
turmoil1530
perturbate1533
broil1548
mis-set?1553
shake1567
parbruilyiec1586
agitate1587
roil1590
transpose1594
discompose1603
harrow1609
hurry1611
obturb1623
shog1636
untune1638
alarm1649
disorder1655
begruntlea1670
pother1692
disconcert1695
ruffle1701
tempestuate1702
rough1777
caddle1781
to put out1796
upset1805
discomfort1806
start1821
faze1830
bother1832
to put aback1833
to put about1843
raft1844
queer1845
rattle1865
to turn over1865
untranquillize1874
hack1881
rock1881
to shake up1884
to put off1909
to go (also pass) through a phase1913
to weird out1970
the mind > emotion > fear > nervousness or uneasiness > be nervous or uneasy (about) [verb (transitive)] > cause to be uneasy
diseasec1384
the mind > emotion > suffering > state of annoyance or vexation > be annoyed or vexed by [verb (transitive)] > annoy or vex
gremec893
dretchc900
awhenec1000
teenOE
fretc1290
annoyc1300
atrayc1320
encumberc1330
diseasec1340
grindc1350
distemperc1386
offenda1387
arra1400
avexa1400
derea1400
miscomforta1400
angerc1400
engrievec1400
vex1418
molesta1425
entrouble?1435
destroublea1450
poina1450
rubc1450
to wring (a person) on the mailsc1450
disprofit1483
agrea1492
trouble1515
grig1553
mis-set?1553
nip?1553
grate1555
gripe1559
spitec1563
fike?1572
gall1573
corsie1574
corrosive1581
touch1581
disaccommodate1586
macerate1588
perplex1590
thorn1592
exulcerate1593
plague1595
incommode1598
affret1600
brier1601
to gall or tread on (one's) kibes1603
discommodate1606
incommodate1611
to grate on or upon1631
disincommodate1635
shog1636
ulcerate1647
incommodiate1650
to put (a person) out of his (her, etc.) way1653
discommodiate1654
discommode1657
ruffle1659
regrate1661
disoblige1668
torment1718
pesta1729
chagrin1734
pingle1740
bothera1745
potter1747
wherrit1762
to tweak the nose of1784
to play up1803
tout1808
rasp1810
outrage1818
worrit1818
werrit1825
buggerlug1850
taigle1865
get1867
to give a person the pip1881
to get across ——1888
nark1888
eat1893
to twist the tail1895
dudgeon1906
to tweak the tail of1909
sore1929
to put up1930
wouldn't it rip you!1941
sheg1943
to dick around1944
cheese1946
to pee off1946
to honk off1970
to fuck off1973
to tweak (a person's or thing's) tail1977
to tweak (a person's or thing's) nose1983
to wind up1984
to dick about1996
to-teen-
c1384 Bible (Wycliffite, E.V.) (Douce 369(2)) (1850) Deeds xv. 19 For which thing I deme hem..for to be not vnquyetid, or disesid [L. inquietari].
c1390 in F. J. Furnivall Minor Poems Vernon MS (1901) ii. 725 Ȝif þou knowe ouȝt þat disese may, ffonde euur more to sey þe beste!
?c1425 (c1412) T. Hoccleve De Regimine Principum (Royal 17 D.vi) (1860) 28 It ruethe me, yf I have you disesede.
1526 Bible (Tyndale) Mark v. f. lv Thy doughter is deed: why deseasest thou the master eny further?
1554 J. Knox Godly Let. sig. A viij He wold not disease hymself to heare a sermon.
1638 W. Chillingworth Relig. Protestants i. iv. §19. 200 That I should disease myself or my Reader with a punctual examination of it, may seem superfluous.
1724 R. Welton 18 Disc. 274 A short skin-deep affliction, which can but disease him for a few moments.
b. transitive. To disturb or startle (a person) from sleep, rest, etc. Obsolete.
ΘΚΠ
the world > physical sensation > sleeping and waking > state of being awake > wake or rouse [verb (transitive)] > specific disturb or startle
diseasec1374
affraya1393
a1413 (c1385) G. Chaucer Troilus & Criseyde (Pierpont Morgan) (1882) iii. l. 1468 And suffrest here [sc. þe Dawyng] so soone vp..ryse For to disesen [c1430 Cambr. Gg.4.27 disese] loueres yn þis wyse.
1483 tr. Adam of Eynsham Reuelation xiii Sum what troubulde & disesyd by the noyse of the couent when they went oute of the chirche.
1568 Newe Comedie Iacob & Esau i. i. sig. A.ijv We disease our tent and neighbours all With rising ouer early.
?1611 G. Chapman tr. Homer Iliads x. 45 Brother, hie thee to thy ships, and Idomen dis-ease, With warlike Ajax.
1655 T. Bayly Life J. Fisher xxii. 202 He was loath to disease him of his rest.
2.
a. transitive. To harm (a person); to affect adversely. Cf. to do disease to at disease n. 1a. Obsolete.
Π
a1387 J. Trevisa tr. R. Higden Polychron. (St. John's Cambr.) (1876) VI. 299 Þis Lowys, for he was so mylde, was ofte disesed [L. perpessus est difficultates] boþe of his owne men and of oþere.
a1393 J. Gower Confessio Amantis (Fairf.) ii. l. 3010 Thou..hast desesed The Court of France be thi wrong.
c1429 Mirour Mans Saluacioune (1986) l. 465 Sometymes diseses man a migge or els a flee.
c1440 W. Hilton Mixed Life (Thornton) in G. G. Perry Eng. Prose Treat. (1921) 43 Ouþer for to put þe fra thi mete or thi slepe..or for to disesse any oþer mane vnskilfully.
a1450 ( tr. Vegetius De Re Militari (Douce) (1988) 131 Sodeyn onfallynge of enemyes..ne schulde neuere haue noyed ne disesed none oostes.
b. transitive. To hurt, inflict pain or physical suffering on (a person). Cf. disease n. 1b Obsolete.
Π
c1410 tr. R. Higden Polychron. (St. John's Cambr.) (1879) VII. 147 By þe space of þo þre dayes he was dissesed [L. infestatum] of þe develes.
a1425 (c1395) Bible (Wycliffite, L.V.) (Royal) (1850) Wisd. xix. 20 Flawmes of corruptible beestis disesiden [E.V. a1382 Douce 369(1) trauaileden; L. vexaverunt] not the fleischis of Ebreis.
?a1430 T. Hoccleve Inuocacio ad Patrem l. 32 in Minor Poems (1970) ii. 276 They..were in prison, In yren bondes greuously disesid.
a1500 (?a1450) Gesta Romanorum (BL Add. 9066) (1879) 368 Then the crowe..disesed the Egle with many betynges.
3.
a. transitive. To cause illness or disease in (a person, animal, plant, part of the body, etc.); to make ill. Also (and in earliest use) in passive: to suffer from or be afflicted by illness or disease.In passive use often not clearly distinguishable from predicative use of diseased adj. 1a.
ΘΚΠ
the world > health and disease > ill health > a disease > affect with disease [verb (transitive)]
a1398 J. Trevisa tr. Bartholomaeus Anglicus De Proprietatibus Rerum (BL Add. 27944) (1975) I. v. ii. 171 Somtyme þe heed is desesed [L. patitur] wiþ an inward cause.
1493 (c1410) Dives & Pauper (Pynson) ix. vi. sig. Giv/1 He hurte his foote and diseasyd al his body.
1577 B. Googe tr. C. Heresbach Foure Bks. Husbandry iv. f. 191 Little children diseased with the dry cough.
a1670 S. Collins Systeme Anat. (1685) i. ii. xxv. 296 Salt recrements diseasing the ventricle..are corrected by Lime-Drinks, which are advised with good success in Diseases arising from gross, and salt humours.
1714 J. Quincy tr. R. Carr Medicinal Epist. iv. 33 Drinking in a Morning will disease and kill a person sooner.
1887 J. Ellis New Christianity iv. 116 No other poison..so perverts, diseases, pollutes and degrades a man,..as does alcohol.
1979 Plant Dis. Reporter 63 365 Some Redhaven [peach] trees..were diseased by natural infections of bacterial canker.
2012 Times 24 Mar. (Mag.) 15/4 Modern washing machines are also quietly diseasing you. Doing the laundry at low temperatures means that bugs such as E. coli aren't killed.
b. transitive. figurative. To have an adverse effect on (a person or thing) in a manner analogous to an illness.
Π
a1637 B. Jonson Eng. Gram. Pref., in Wks. (1640) III Wee free our Language from the opinion of Rudenesse, and Barbarisme, wherewith it is mistaken to be diseas'd.
c1680 E. Hickeringill Hist. Whiggism in Wks. (1716) I. 143 Evil Ministers Disease the Common-wealth.
1798 Oracle & Public Advertiser 29 May An universal phrenzy has diseased the human mind.
1865 W. E. H. Lecky Hist. Rationalism II. vi. 408 Those ghastly notions..which..diseased the imaginations..of men.
1960 Chicago Defender 23 Jan. 23/1 The run and shoot developments that have diseased the sport [sc. basketball].
2014 O. Frawley Flight v. 142 There are already many small children in second-hand prams with rust diseasing the chrome handlebars.
This entry has been updated (OED Third Edition, December 2022).
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