amelanosisn.
/ˌeɪmɛləˈnəʊsɪs/, U.S. /ˌeɪˌmɛləˈnoʊsəs/, /əˌmɛləˈnoʊsəs/ Absence of the dark pigment melanin (in a melanoma or in tissues of the body where it is normally present); lack of pigmentation resulting from this.
ΚΠ
1948 Brit. Jrnl. Cancer 2 124 The loss of characteristic enzyme systems, that is in secondary regressive mutation and dedifferentiation—such as the amelanosis of a melanoma or the loss of the stilboestrol reaction by prostate cells.
1989 Poultry Sci. 68 1320/1 All the birds used in these matings showed extensive feather amelanosis and were, therefore, essentially white.
2003 Rev. Gynaecol. Pract. 3 209/2 The main predictors of survival were tumour thickness (as measured by Breslow system), ulceration, and macroscopic amelanosis.
This entry has been updated (OED Third Edition, March 2020; most recently modified version published online December 2021).
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n.1948