| 单词 | alpha-methyldopa |
| 释义 | > as lemmasalpha-methyldopa methyldopa n. Pharmacology (more fully alpha-methyldopa) the compound 3-(3,4-dihydroxyphenyl)-2-methyl-L-alanine, C10H13NO4, which is used as an antihypertensive agent. ΘΚΠ the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations treating or preventing specific ailments > [noun] > for blood-pressure disorders Neo-Synephrine1934 Priscol1938 phenylephrine1947 hexamethonium1949 Priscoline1949 methonium1950 hydralazine1952 phentolamine1953 methyldopa1954 pentolinium1954 mecamylamine1955 hydrochlorothiazide1958 pempidine1958 guanethidine1959 hydroflumethiazide1959 thiazide1959 pheniprazine1960 pargyline1961 vasodepressor1961 alpha blocker1965 clonidine1969 prazosin1970 timolol1973 1954 Arch. Biochem. & Biophysics 51 456 Two compounds, α-methyl-3,4-dopa (α-MD) and α-methyl-3-hydroxyphenylalanine, respectively, added in a low range of concentrations, accelerated, and at higher concentrations, inhibited, kidney dopa decarboxylase. 1961 N.Z. Med. Jrnl. 60 569/2 Methyl dopa, like other potent hypotensive agents, produces side-effects including fatigue. 1972 Materials & Technol. V. xxi. 792 Methyldopa and pargyline cause the replacement of noradrenaline by a weaker transmitter. 1984 M. J. Taussig Processes in Pathol. & Microbiol. (ed. 2) ii. 92 For instance, α-methyldopa, a drug used in treatment of hypertension, induces autoimmune haemolytic anaemia. 2000 S. Afr. Med. Jrnl. 90 156 Methyldopa was the antihypertensive used most frequently for the treatment of mild to moderate hypertension. < as lemmas |
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