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单词 ethosuximide
释义

ethosuximiden.

Brit. /ˌɛθə(ʊ)sʌkˈsɪmʌɪd/, U.S. /ˌɛθoʊˌsəkˈsɪˌmaɪd/, /ˌɛθəˌsəkˈsɪˌmaɪd/
Origin: Formed within English, by compounding. Etymons: eth- comb. form, -o- connective, sux- comb. form, imide n.
Etymology: < eth- comb. form + -o- connective + sux- comb. form + imide n. Compare earlier succinimide n.
Pharmacology.
An anticonvulsant drug, used esp. in the treatment of petit mal epilepsy.Chemical name: 2-ethyl-2-methylsuccinimide; C7H11NO2.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > sedatives, antispasmodics, etc. > [noun] > antispasmodic or anticonvulsant > specific substances or preparations
Dilantin1938
phenytoin1942
Artane1948
Mysoline1949
mephenesin1952
troxidone1952
primidone1953
acetazolamide1954
orphenadrine1957
tetrabenazine1958
ethosuximide1960
methsuximide1965
clonazepam1970
valproic1972
valproate1974
1960 Lancet 3 Dec. 1258/2 (table) Ethosuximide[.] α-Ethyl-α-methylsuccinimide[.] Zarontin.
1977 Lancet 3 Sept. 509/2 Seven outpatients, six with epilepsy and one with trigeminal neuralgia who had been treated with carbamazepine alone or in combination with phenobarbitone, clonazepam or ethosuximide.
1987 M. J. Neal Med. Pharmacol. at Glance xxiii. 52/2 Absence seizures are usually treated with ethosuximide.
2005 Daily Tel. 17 Jan. 22/4 The anticonvulsant drug ethosuximide (Zarontin) used to treat epileptic seizures extended the worms' life span.
This entry has been updated (OED Third Edition, March 2014; most recently modified version published online March 2022).
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n.1960
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