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单词 fetoprotein
释义

fetoproteinn.

Brit. /ˌfiːtə(ʊ)ˈprəʊtiːn/, U.S. /ˌfidoʊˈproʊˌtin/
Forms: 1900s– fetoprotein, 1900s– foetoprotein.
Origin: Formed within English, by compounding; modelled on a Russian lexical item. Etymons: fetus n., -o- connective, protein n.
Etymology: < fetus n. + -o- connective + protein n., after Russian fetoprotein (1964 in the source translated in quot. 1964), itself after French foeto-protéine (G. de Muralt & D. L. A. Roulet 1961, in Helvetica Paediatrica Acta 16 517).
Biochemistry.
A protein present in fetal serum; spec. (more fully alpha-fetoprotein) a glycoprotein which is the predominant serum protein of the fetus and can also be detected in amniotic fluid and maternal blood, in which an elevated level is associated ​with certain congenital abnormalities of the fetus, esp. spina bifida and anencephaly; abbreviated AFP.Alpha-fetoprotein is also an oncofetal antigen, found at an elevated level in the blood of persons with certain cancers and other diseases, esp. of the liver.
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the world > life > biology > substance > proteins > [noun]
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orosomucoid1955
metallothionein1960
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aequorin1962
ferredoxin1962
LDL1962
fetoprotein1964
thioredoxin1964
actinin1965
adrenodoxin1965
lactoferrin1965
myoglobulin1965
rubredoxin1965
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1964 Excerpta Medica Sect. 10: Obstetr. & Gynaecol. 17 948 The beta-fetoprotein, which has been discovered, has not yet been identified.
1965 Annales Pediatrici 204 139 After being isolated from human fetal sera the fetoprotein was found to be insoluble in perchloric acid.
1966 D. Gitlin & M. Boesman in Jrnl. Pediatrics 69 899/2 The serum of the human conceptus contains a protein which is not present in children or adults. The protein migrates between albumin and α1-globulin on electrophoresis, and may be termed α-fetoprotein.
1980 Lancet 16 Feb. 339/2 All mothers with raised amniotic fluid alpha-fetoprotein values..accepted termination of pregnancy.
2002 Times 16 July (Good Birth Guide Suppl.) 5/6 Alfa-fetoprotein (AFP): low levels indicate Down's syndrome; very high indicate spina bifida or anencephaly.
This is a new entry (OED Third Edition, September 2012; most recently modified version published online March 2022).
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n.1964
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