filgrastimn.

Brit.

/fɪlˈɡrastɪm/, U.S.

/fɪlˈɡræstɪm/

Origin: Formed within English, by compounding. Etymons: neutrophil adj., granulocyte n., stimulating adj.

Etymology: < fil- (perhaps representing -phil in neutrophil adj.) + -gra- (in granulocyte n.) + -stim (in stimulating adj.): compare granulocyte colony-stimulating factor n. at granulocyte n. Additions.

Pharmacology.

A form of human granulocyte colony-stimulating factor produced by recombinant DNA technology, used chiefly for the treatment of chemotherapy-induced neutropenia; also called Neupogen.Filgrastim is a non-glycosylated protein containing an added N-terminal methionine residue.

ΚΠ

1991 Drug Topics 8 Apr. 22/1 Recombinant G-CSF (filgrastim), aimed at decreasing the frequency and severity of chemotherapy-induced neutropenia, was approved in February.

1997 Denver Post (Nexis) 4 Feb. b2 As a result, [HIV-infected] patients treated with Filgrastim had 45 percent fewer hospital days for bacterial infection over the 24-week study period.

2001 N.Y. Rev. Bks. 11 Jan. 46/2 Neupogen, a registered trademark of filgrastim, a granulocyte-colony-stimulating recombinant DNA drug.

This is a new entry (OED Third Edition, September 2003; most recently modified version published online March 2022).

单词	filgrastim
释义	filgrastimn. Brit. /fɪlˈɡrastɪm/, U.S. /fɪlˈɡræstɪm/ Origin: Formed within English, by compounding. Etymons: neutrophil adj., granulocyte n., stimulating adj. Etymology: < fil- (perhaps representing -phil in neutrophil adj.) + -gra- (in granulocyte n.) + -stim (in stimulating adj.): compare granulocyte colony-stimulating factor n. at granulocyte n. Additions. Pharmacology. A form of human granulocyte colony-stimulating factor produced by recombinant DNA technology, used chiefly for the treatment of chemotherapy-induced neutropenia; also called Neupogen.Filgrastim is a non-glycosylated protein containing an added N-terminal methionine residue. ΚΠ 1991 Drug Topics 8 Apr. 22/1 Recombinant G-CSF (filgrastim), aimed at decreasing the frequency and severity of chemotherapy-induced neutropenia, was approved in February. 1997 Denver Post (Nexis) 4 Feb. b2 As a result, [HIV-infected] patients treated with Filgrastim had 45 percent fewer hospital days for bacterial infection over the 24-week study period. 2001 N.Y. Rev. Bks. 11 Jan. 46/2 Neupogen, a registered trademark of filgrastim, a granulocyte-colony-stimulating recombinant DNA drug. This is a new entry (OED Third Edition, September 2003; most recently modified version published online March 2022). < n.1991
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