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单词 fluconazole
释义

fluconazolen.

Brit. /flᵿˈkɒnəzəʊl/, U.S. /fluˈkɑnəˌzoʊl/
Origin: Formed within English, by compounding. Etymons: fluoro- comb. form, English miconazole.
Etymology: < flu- (in fluoro- comb. form) + -conazole (in miconazole (1970 or earlier), the name of an earlier antimycotic drug of related structure; of uncertain origin, perhaps < mico- , respelling of myco- comb. form + -n- (in nitrate n., nitro- comb. form) + -azole comb. form).
Pharmacology.
An antifungal drug that can be given orally and is often used in the treatment of opportunistic infections in immunosuppressed persons, such as those with AIDS.Fluconazole is a tricyclic compound with one difluorophenyl and two triazole groups.Systematic name: 2-(2,4-difluorophenyl)-1,3-bis(1H-1,2,4 triazol-1-yl)-propan-2-ol; C13H12F2N6O.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > remedies for parasitic infections > [noun] > fungicide
thiram1950
nystatin1952
amphotericin1956
prochloraz1977
fluconazole1985
1985 Antimicrobial Agents & Chemotherapy 28 648 The pharmacokinetic profile of UK-49,858 (fluconazole), a novel triazole antifungal agent which is being developed for oral and intravenous use, was determined.
1992 N.Y. Times Mag. 5 Jan. 12/4 There are new drugs to treat AIDS-related infections, including the drug foscarnet for an eye disorder caused by a cytomegalovirus, and fluconazole to treat fungal infections.
2003 New Yorker 29 May 59/2 His doctor told him that an expensive drug called fluconazole could treat his opportunistic infection.
This is a new entry (OED Third Edition, March 2012; most recently modified version published online March 2022).
<
n.1985
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