单词 | forward mutation |
释义 | > as lemmasforward mutation forward mutation n. Genetics mutation that results in a change in the original or normal (wild type) phenotype or genotype; an instance of this; cf. earlier back mutation n. at back adj. Additions, reverse mutation n. at reverse adj. and adv. Compounds 2. ΚΠ 1939 Amer. Naturalist 73 313 Some genes..show more or less equal rates of back and forward mutation. 1956 Brookhaven Symp. Biol. (1957) 8 103 These studies involve changes occurring in both directions: so-called forward (or direct) mutations from the wild type..to the mutant..phenotype, and back (reverse) mutation from the auxotrophic to the prototrophic phenotype. 1978 Nature 31 Aug. 891/1 Forward mutations at a variety of loci in rad 1–1 yeast are also subject to photorepair. 2002 Jrnl. Biol. Chem. 277 22345 The increase in fidelity of the F61A mutant [reverse transcriptase] was corroborated by a 12-fold decrease in its forward mutation rate. < as lemmas |
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