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单词 gentamicin
释义

gentamicinn.

Brit. /ˌdʒɛntəˈmʌɪsɪn/, U.S. /ˌdʒɛntəˈmaɪsᵻn/
Forms: 1900s– gentamicin, 1900s– gentamycin.
Origin: Of uncertain origin. Perhaps formed within English, by compounding. Etymons: gentian violet n. at gentian n. and adj. Compounds 2, gentian n., English -micin , -mycin suffix.
Etymology: Origin uncertain. Perhaps < gent- (in either gentian violet n. at gentian n. and adj. Compounds 2 or gentian n., although the microorganisms producing the antibiotic are in fact variously coloured) + -micin, alteration of -mycin suffix.
Pharmacology.
An aminoglycoside antibiotic that consists of a mixture of several substances produced by soil- or mud-dwelling microorganisms (actinomycetes) of the genus Micromonospora, and is used in the treatment of severe infections with Gram-negative and some Gram-positive bacteria.Like other aminoglyosides, gentamicin is not absorbed from the gastrointestinal tract and is administered by injection, and may have damaging side-effects on the kidneys and inner ear.
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the world > life > biology > substance > process stimulators or inhibitors > antibiotic > [noun]
actinomycin1940
claviformin1942
antibiotic1944
bacteriocin1954
gentamicin1963
rishitin1968
magainin1987
1963 Jrnl. Medicinal Chem. 6 463/2 When these organisms are grown in submerged culture in a yeast extract-cerelose medium they produce gentamicin and other basic antibiotics.
1977 Ann. Internal Med. 86 469/1 If nephrotoxic agents with narrow therapeutic ratios such as gentamicin are used, we currently recommend that serum levels be monitored.
1999 Guardian 23 Feb. i. 1/8 The most common drugs given to these tiny sick babies were gentamicin and benzyl penicillin, which are used in septicaemia and meningitis.
2017 Times (Nexis) 4 Mar. (Mag.) 13 Since 2015, when I got an intravenous injection of the powerful antibiotic gentamicin, I have been mercifully free of E. coli infections.
This entry has been updated (OED Third Edition, March 2021; most recently modified version published online March 2022).
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n.1963
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