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antimelancholic
antimelancholic adj. and n. 
/ˌantɪmɛləŋˈkɒlɪk/, /ˌænˌtaɪˌmɛlənˈkɑlɪk/, /ˌæn(t)əˌmɛlənˈkɑlɪk/
Brit. /ˌantɪmɛlənˈkɒlɪk/
, /ˌantɪmɛlənˈkɒlɪk//ˌantɪmɛləŋˈkɒlɪk/U.S. /ˌæn(t)iˌmɛlənˈkɑlɪk/
, /ˌæn(t)iˌmɛlənˈkɑlɪk//ˌænˌtaɪˌmɛlənˈkɑlɪk//ˌæn(t)əˌmɛlənˈkɑlɪk/ΚΠ
1704 tr. G. Baglivi Pract. Physick i. xiv. 184 For the Remedies in the Apothecaries Shops, that go by the Name of Exhilarating, Antimelancholick [L. antimelancolica], Comforters of the Heart and Memory, Whets for the Genius, &c. are rather invented to favour the Pomp of the Art, than to dispel the bitter Cares of the Mind, or to rouze a drooping Spirit.
1877 R. Hughes Man. Therapeutics (ed. 2) i. xiii. 181 Aurum..is also a well-known anti-melancholic.
1998 New Eng. Q. 71 268 One drug that would soon be hailed (erroneously, it would be discovered) as an effective anti-melancholic, cocaine, had only just made its appearance in the United States.
2007 C. M. Swartz & E. Shorter Psychotic Depression 275 It [sc. bupropion] is a first choice antimelancholic drug for males over age 40 who have no seizure risk.
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