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单词 guanase
释义

guanasen.

/ˈɡwɑːneɪz//ˈɡwɑːneɪs/
Etymology: < German guanase (Jones & Partridge 1904, in Hoppe-Seyler's Zeitschr. f. Physiol. Chem. XLII. 347), < guan- (in guanine n.) + -ase suffix.
Biochemistry.
An enzyme that hydrolyses guanine to xanthine and ammonia; guanine aminohydrolase, guanine deaminase.
ΚΠ
1904 Jrnl. Chem. Soc. 86 i. 838 Fresh pancreas, when subjected to autolysis, does not yield adenine or guanine, and guanine which is added is transformed into xanthine within 3 days. The enzyme present in pancreas which induces this change is termed Guanase.
1967 Biochem. Jrnl. 104 634/1 Guanase (guanine aminohydrolase, EC 3.5.4.3) was of special interest as guanine is metabolically a precursor of xanthine and is thus indirectly a source of uric acid.
This entry has not yet been fully updated (first published 1933; most recently modified version published online September 2018).
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