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单词 guanethidine
释义

guanethidinen.

/ɡwəˈnɛθɪdiːn/
Etymology: < guanidine n., by insertion of -eth- (in ethyl n.).
Pharmacology.
A drug, 2-(octahydro-1-azocinyl)-ethyl guanidine, used to reduce blood pressure.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations treating or preventing specific ailments > [noun] > for blood-pressure disorders
Neo-Synephrine1934
Priscol1938
phenylephrine1947
hexamethonium1949
Priscoline1949
methonium1950
hydralazine1952
phentolamine1953
methyldopa1954
pentolinium1954
mecamylamine1955
hydrochlorothiazide1958
pempidine1958
guanethidine1959
hydroflumethiazide1959
thiazide1959
pheniprazine1960
pargyline1961
vasodepressor1961
alpha blocker1965
clonidine1969
prazosin1970
timolol1973
1959 Jrnl. Amer. Med. Assoc. 11 July 1265/1 The former has been given the generic name guanethidine by the manufacturer.
1959 Lancet 12 Dec. 1048/2 The hypotensive action of guanethidine appears to be due to selective blockade of the sympathetic nervous system.
1970 Jrnl. Pharmacol. & Exper. Therapeutics 173 166/1 Reserpine and guanethidine prevented the glandular enlargement induced by papain or amputation.
This entry has not yet been fully updated (first published 1972; most recently modified version published online June 2018).
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n.1959
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