haemoglobinhemoglobinn.

/hiːməʊˈɡləʊbɪn/

Etymology: Shortened < haemato-globulin n. Compare German Hämoglobin.

Chemistry.

The colouring matter of the red corpuscles of the blood, which serves to convey oxygen to the tissues in the circulation; it is a protein which is resolvable into hæm and globin; when oxidized ( oxyhaemoglobin) it has a bright scarlet colour, and is crystallizable. Formerly called cruorin, hæmatoglobulin, hæmoglobulin, hæmatoglobin. Also attributive and in other combinations.

ΘΚΠ

the world > life > the body > vascular system > blood > components of blood > blood corpuscle or plate > [noun] > red cells or corpuscles > haemoglobin

cruorin1840

haemato-globulin1845

haemoglobin1869

haemoglobulin1876

1869 Biennial Retrospect (New Sydenham Soc.) 3 The specific gravity of hæmoglobin may by calculation be approximately estimated as 1 . 2 to 1 . 3.

1869–72 H. Watts Dict. Chem. VI. 352 Hæmoglobin, Hæmatoglobin, this substance is the only colouring matter of the blood of vertebrate animals.

1869–72 H. Watts Dict. Chem. VI. 353 Hæmoglobin is the only ferruginous constituent of the blood-corpuscles.

1872 T. H. Huxley Lessons Elem. Physiol. (ed. 6) iii. 65 Called hæmoglobin from its readily breaking up into globulin and hæmatin.

1876 J. Van Duyn & E. C. Seguin tr. E. L. Wagner Man. Gen. Pathol. 310 Hæmoglobin..or Hæmatoglobulin..consists of an albumen and a colouring matter hæmatin.

1886 New Sydenham Soc. Lexicon Hæmoglobin..is a colloid, but when combined with oxygen, as oxyhæmoglobin, crystallises according to the rhombic system in plates, or prisms, or tetrahedra..they are bluish red by transmitted light, scarlet by reflected light.

1907 Yesterday's Shopping (1969) 510/1 Hæmoglobin Tablets.

1950 Sci. News 15 96 But these lake-dwelling Daphnia, if deprived of abundant oxygen in the laboratory, also become pink with newly-formed hæmoglobin in their blood. Thus they have the capacity of hæmoglobin synthesis when stimulated by lack of oxygen, although they do not profit by this gift in nature.

1950 Sci. News 15 103 Hæmoglobin is unusual among proteins in having a coloured part of its molecule, a coloured part with characteristic absorption bands in its spectrum which can be measured.

1956 Nature 17 Mar. 524/1 There was a drop in the hæmoglobin-level from 81 to 70 per cent when tested by the Sahli method.

1956 New Biol. 21 55 Sickle-cell haemoglobin is the best known of the abnormal haemoglobins in man, but several other types can be distinguished by electrophoretic and solubility tests. These are known as haemoglobin types C, D, E, G, H, I, J, K, and M.

1957 New Biol. 24 61 The mean of the twenty values on the scale gives the ‘haemoglobin index’ of the population.

1963 R. P. Dales Annelids iv. 81 Haemoglobin-containing corpuscles are distributed in the coelomic fluid.

1964 G. H. Haggis et al. Introd. Molecular Biol. v. 115 In the red blood cell it is the only structure observed between the haemoglobin-laden cytoplasm and the blood plasma.

1968 H. Harris Nucleus & Cytoplasm vi. 118 The failure of high concentrations of actinomycin D to inhibit decisive events in the differentiation of colonial myxamoebae, of pancreatic cells in the mouse embryo, and of haemoglobin-forming cells in the chick embryo.

1968 Times 17 May (heading) Structure of haemoglobin solved.

Derivatives

ˌhaemoglobiˈnaemia n. /-ˈniːmɪə/ [ < haemoglobin n. and Greek αἷμα blood, after anæmia, etc.] Pathology the presence of free hæmoglobin in the fluid part of the blood.

ΘΚΠ

the world > health and disease > ill health > a disease > disorders of internal organs > disorders of blood > [noun] > presence of abnormalities

piarhaemia1848

uraemia1853

melanaemia1859

urinaemia1860

lithaemia1874

lipaemia1881

blood urea1883

haemoglobinaemia1885

bacteraemia1890

oxalaemia1892

uric-acidaemia1893

sulphaemoglobinaemia1910

carotenaemia1919

parasitaemia1944

viraemia1947

paraproteinaemia1956

1885 W. Roberts Urinary & Renal Dis. (ed. 4) iv. 162 (note) The so-called ‘Hæmoglobinæmia’ which precedes the change in the urine.

1886 New Sydenham Soc. Lexicon Hæmoglobinhæmia, the condition in which hæmoglobin is diffused into the liquor sanguinis, as occurs in some cases of hæmophilia.

ˌhaemoglobiˈniferous adj. [see -ferous comb. form] containing hæmoglobin.

ΚΠ

1884 Encycl. Brit. XVII. 329/2 The blood fluid is often provided with hæmoglobiniferous disks.

ˌhaemoglobiˈnometer n. [compare German Häoglobinometer (1880); compare -meter comb. form²] an instrument for measuring the quantity of hæmoglobin in blood.

ΚΠ

1885 W. Stirling tr. L. Landois Text-bk. Human Physiol. I. 26 The hæmoglobinometer of Gowers is used for the clinical estimation of hæmoglobin.

ˌhaemoglobiˈnometry n. the measurement of this.

ΘΚΠ

the world > health and disease > healing > diagnosis or prognosis > specific measuring or recording > [noun]

arteriography1833

pulmometry1835

pneumometry1853

sphygmography1859

spirometry1859

sphygmometry1867

pneumatometry1876

stethography1876

stethometry1876

cephalometry1881

haemautography1885

haemoglobinometry1887

pelvigraphy1890

plethysmography1890

sphygmomanometry1905

electrocardiography1910

phlebography1912

phonocardiography1913

T.P.R.1917

Fick('s) principle1920

pneumography1921

polygraphy1923

electromyography1926

oscillometry1927

pneumotachography1930

electroencephalography1935

oximetry1944

vectorcardiography1946

ballistocardiography1950

tympanometry1956

thermography1957

cystometry1959

spirography1959

rheograph1960

magnetocardiography1967

Fick method1968

magnetoencephalography1968

biofeedback1970

tympanography1977

1887 Brit. Med. Jrnl. 9 July 80 Hæmoglobinometry.

1961 B.S.I. News Dec. 27 (heading) Sealed glass cells for photometric hæmoglobinometry.

ˌhaemoglobiˈnopathy n. any condition in which the quality of the hæmoglobin in the blood is defective.

ΘΚΠ

the world > health and disease > ill health > a disease > disorders of internal organs > disorders of blood > [noun] > deficiency of other substances

hypinosis1845

anaemotrophy1860

hypoglycaemia1894

hypoleucocytosis1897

acapnia1898

leucopenia1898

hypothyroidism1905

hypocapnia1908

lymphopenia1909

hypoparathyroidism1910

neutropenia1915

thrombopenia1915

thrombocytopenia1921

agranulocytosis1923

hypocalcaemia1925

insulin shock1925

hypochloraemia1927

granulocytopenia1931

hypopotassaemia1932

hypomagnesaemia1933

hypoproteinaemia1934

hyponatraemia1935

hypophosphataemia1935

hypoprothrombinaemia1936

hypoalbuminaemia1937

sideropenia1938

afibrinogenaemia1941

pancytopenia1941

hypokalaemia1949

agammaglobulinaemia1952

hypogammaglobulinaemia1955

haemoglobinopathy1957

1957 A. W. Woodruff et al. in Brit. Med. Jrnl. 25 May 1235/1 (heading) Terminology of the hereditary haemoglobinopathies with haemoglobin variants.

1957 A. W. Woodruff et al. in Brit. Med. Jrnl. 25 May 1235/2 The term haemoglobinopathy should be used to denote a condition in which the production of normal adult haemoglobin..is partly or wholly suppressed and it is partly or wholly replaced by one or more haemoglobin variants.

1962 Lancet 12 May 1006/2 As the hæmoglobinopathies grow in importance, a monograph taking stock of what we know of thalassæmia is welcome.

1966 Lancet 31 Dec. 1435/1 The situation with respect to diabetes reminds one of attempts to analyse the hæmoglobinopathies before chemical techniques were available for the identification of hæmoglobins to discriminate between possible genotypes.

ˌhaemoglobiˈnuria n. /-ˈjʊərɪə/ [Greek οὖρον urine] Pathology the presence of free hæmoglobin in the urine.

ΘΚΠ

the world > health and disease > ill health > a disease > disorders of internal organs > urinary disorders > [noun] > blood in urine

bloody water1607

haematuria1811

haematinuria1879

haemoglobinuria1881

1881 A. Flint Treat. Princ. Med. (ed. 5) 923 A pathological condition of the blood stands in an immediate causative relation to the haemoglobinuria in this affection.

ˌhaemoglobiˈnuric adj. characterized by hæmoglobinuria.

ΘΚΠ

the world > health and disease > ill health > a disease > disorders of internal organs > urinary disorders > [adjective] > blood in urine

haematuric1866

haemoglobinuric1893

1893 A. Davidson Hygiene & Dis. Warm Climates 181 Bilious hæmoglobinuric fever is met with in Madagascar, Mauritius..and some parts of Italy.

This entry has not yet been fully updated (first published 1898; most recently modified version published online December 2018).

单词	haemoglobin
释义	haemoglobinhemoglobinn. /hiːməʊˈɡləʊbɪn/ Etymology: Shortened < haemato-globulin n. Compare German Hämoglobin. Chemistry. The colouring matter of the red corpuscles of the blood, which serves to convey oxygen to the tissues in the circulation; it is a protein which is resolvable into hæm and globin; when oxidized ( oxyhaemoglobin) it has a bright scarlet colour, and is crystallizable. Formerly called cruorin, hæmatoglobulin, hæmoglobulin, hæmatoglobin. Also attributive and in other combinations. ΘΚΠ the world > life > the body > vascular system > blood > components of blood > blood corpuscle or plate > [noun] > red cells or corpuscles > haemoglobin cruorin1840 haemato-globulin1845 haemoglobin1869 haemoglobulin1876 1869 Biennial Retrospect (New Sydenham Soc.) 3 The specific gravity of hæmoglobin may by calculation be approximately estimated as 1 . 2 to 1 . 3. 1869–72 H. Watts Dict. Chem. VI. 352 Hæmoglobin, Hæmatoglobin, this substance is the only colouring matter of the blood of vertebrate animals. 1869–72 H. Watts Dict. Chem. VI. 353 Hæmoglobin is the only ferruginous constituent of the blood-corpuscles. 1872 T. H. Huxley Lessons Elem. Physiol. (ed. 6) iii. 65 Called hæmoglobin from its readily breaking up into globulin and hæmatin. 1876 J. Van Duyn & E. C. Seguin tr. E. L. Wagner Man. Gen. Pathol. 310 Hæmoglobin..or Hæmatoglobulin..consists of an albumen and a colouring matter hæmatin. 1886 New Sydenham Soc. Lexicon Hæmoglobin..is a colloid, but when combined with oxygen, as oxyhæmoglobin, crystallises according to the rhombic system in plates, or prisms, or tetrahedra..they are bluish red by transmitted light, scarlet by reflected light. 1907 Yesterday's Shopping (1969) 510/1 Hæmoglobin Tablets. 1950 Sci. News 15 96 But these lake-dwelling Daphnia, if deprived of abundant oxygen in the laboratory, also become pink with newly-formed hæmoglobin in their blood. Thus they have the capacity of hæmoglobin synthesis when stimulated by lack of oxygen, although they do not profit by this gift in nature. 1950 Sci. News 15 103 Hæmoglobin is unusual among proteins in having a coloured part of its molecule, a coloured part with characteristic absorption bands in its spectrum which can be measured. 1956 Nature 17 Mar. 524/1 There was a drop in the hæmoglobin-level from 81 to 70 per cent when tested by the Sahli method. 1956 New Biol. 21 55 Sickle-cell haemoglobin is the best known of the abnormal haemoglobins in man, but several other types can be distinguished by electrophoretic and solubility tests. These are known as haemoglobin types C, D, E, G, H, I, J, K, and M. 1957 New Biol. 24 61 The mean of the twenty values on the scale gives the ‘haemoglobin index’ of the population. 1963 R. P. Dales Annelids iv. 81 Haemoglobin-containing corpuscles are distributed in the coelomic fluid. 1964 G. H. Haggis et al. Introd. Molecular Biol. v. 115 In the red blood cell it is the only structure observed between the haemoglobin-laden cytoplasm and the blood plasma. 1968 H. Harris Nucleus & Cytoplasm vi. 118 The failure of high concentrations of actinomycin D to inhibit decisive events in the differentiation of colonial myxamoebae, of pancreatic cells in the mouse embryo, and of haemoglobin-forming cells in the chick embryo. 1968 Times 17 May (heading) Structure of haemoglobin solved. Derivatives ˌhaemoglobiˈnaemia n. /-ˈniːmɪə/ [ < haemoglobin n. and Greek αἷμα blood, after anæmia, etc.] Pathology the presence of free hæmoglobin in the fluid part of the blood. ΘΚΠ the world > health and disease > ill health > a disease > disorders of internal organs > disorders of blood > [noun] > presence of abnormalities piarhaemia1848 uraemia1853 melanaemia1859 urinaemia1860 lithaemia1874 lipaemia1881 blood urea1883 haemoglobinaemia1885 bacteraemia1890 oxalaemia1892 uric-acidaemia1893 sulphaemoglobinaemia1910 carotenaemia1919 parasitaemia1944 viraemia1947 paraproteinaemia1956 1885 W. Roberts Urinary & Renal Dis. (ed. 4) iv. 162 (note) The so-called ‘Hæmoglobinæmia’ which precedes the change in the urine. 1886 New Sydenham Soc. Lexicon Hæmoglobinhæmia, the condition in which hæmoglobin is diffused into the liquor sanguinis, as occurs in some cases of hæmophilia. ˌhaemoglobiˈniferous adj. [see -ferous comb. form] containing hæmoglobin. ΚΠ 1884 Encycl. Brit. XVII. 329/2 The blood fluid is often provided with hæmoglobiniferous disks. ˌhaemoglobiˈnometer n. [compare German Häoglobinometer (1880); compare -meter comb. form²] an instrument for measuring the quantity of hæmoglobin in blood. ΚΠ 1885 W. Stirling tr. L. Landois Text-bk. Human Physiol. I. 26 The hæmoglobinometer of Gowers is used for the clinical estimation of hæmoglobin. ˌhaemoglobiˈnometry n. the measurement of this. ΘΚΠ the world > health and disease > healing > diagnosis or prognosis > specific measuring or recording > [noun] arteriography1833 pulmometry1835 pneumometry1853 sphygmography1859 spirometry1859 sphygmometry1867 pneumatometry1876 stethography1876 stethometry1876 cephalometry1881 haemautography1885 haemoglobinometry1887 pelvigraphy1890 plethysmography1890 sphygmomanometry1905 electrocardiography1910 phlebography1912 phonocardiography1913 T.P.R.1917 Fick('s) principle1920 pneumography1921 polygraphy1923 electromyography1926 oscillometry1927 pneumotachography1930 electroencephalography1935 oximetry1944 vectorcardiography1946 ballistocardiography1950 tympanometry1956 thermography1957 cystometry1959 spirography1959 rheograph1960 magnetocardiography1967 Fick method1968 magnetoencephalography1968 biofeedback1970 tympanography1977 1887 Brit. Med. Jrnl. 9 July 80 Hæmoglobinometry. 1961 B.S.I. News Dec. 27 (heading) Sealed glass cells for photometric hæmoglobinometry. ˌhaemoglobiˈnopathy n. any condition in which the quality of the hæmoglobin in the blood is defective. ΘΚΠ the world > health and disease > ill health > a disease > disorders of internal organs > disorders of blood > [noun] > deficiency of other substances hypinosis1845 anaemotrophy1860 hypoglycaemia1894 hypoleucocytosis1897 acapnia1898 leucopenia1898 hypothyroidism1905 hypocapnia1908 lymphopenia1909 hypoparathyroidism1910 neutropenia1915 thrombopenia1915 thrombocytopenia1921 agranulocytosis1923 hypocalcaemia1925 insulin shock1925 hypochloraemia1927 granulocytopenia1931 hypopotassaemia1932 hypomagnesaemia1933 hypoproteinaemia1934 hyponatraemia1935 hypophosphataemia1935 hypoprothrombinaemia1936 hypoalbuminaemia1937 sideropenia1938 afibrinogenaemia1941 pancytopenia1941 hypokalaemia1949 agammaglobulinaemia1952 hypogammaglobulinaemia1955 haemoglobinopathy1957 1957 A. W. Woodruff et al. in Brit. Med. Jrnl. 25 May 1235/1 (heading) Terminology of the hereditary haemoglobinopathies with haemoglobin variants. 1957 A. W. Woodruff et al. in Brit. Med. Jrnl. 25 May 1235/2 The term haemoglobinopathy should be used to denote a condition in which the production of normal adult haemoglobin..is partly or wholly suppressed and it is partly or wholly replaced by one or more haemoglobin variants. 1962 Lancet 12 May 1006/2 As the hæmoglobinopathies grow in importance, a monograph taking stock of what we know of thalassæmia is welcome. 1966 Lancet 31 Dec. 1435/1 The situation with respect to diabetes reminds one of attempts to analyse the hæmoglobinopathies before chemical techniques were available for the identification of hæmoglobins to discriminate between possible genotypes. ˌhaemoglobiˈnuria n. /-ˈjʊərɪə/ [Greek οὖρον urine] Pathology the presence of free hæmoglobin in the urine. ΘΚΠ the world > health and disease > ill health > a disease > disorders of internal organs > urinary disorders > [noun] > blood in urine bloody water1607 haematuria1811 haematinuria1879 haemoglobinuria1881 1881 A. Flint Treat. Princ. Med. (ed. 5) 923 A pathological condition of the blood stands in an immediate causative relation to the haemoglobinuria in this affection. ˌhaemoglobiˈnuric adj. characterized by hæmoglobinuria. ΘΚΠ the world > health and disease > ill health > a disease > disorders of internal organs > urinary disorders > [adjective] > blood in urine haematuric1866 haemoglobinuric1893 1893 A. Davidson Hygiene & Dis. Warm Climates 181 Bilious hæmoglobinuric fever is met with in Madagascar, Mauritius..and some parts of Italy. This entry has not yet been fully updated (first published 1898; most recently modified version published online December 2018). < n.1869
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