heparinn.

Brit.

/ˈhɛpərɪn/, U.S.

/ˈhɛpərən/

Etymology: < hepar n. + -in suffix¹.

Biochemistry.

A sulphated polysaccharide present in various body tissues and organs, esp. the liver, lungs, and muscles, and used therapeutically as an anti-coagulant.

ΘΚΠ

the world > health and disease > healing > medicines or physic > medical preparations of specific origin > biological product > [noun] > specific

lardc1420

sevumc1440

larding1582

protamine1874

renin1894

serum1895

sturine1896

iodothyrin1897

zymin1901

heparin1918

antireticular cytotoxic serum1942

urokinase1952

cryoprecipitate1956

xenoantiserum1973

anti-serum-

the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations for treating specific parts > [noun] > for the blood > anti-coagulants

anti-coagulant1905

heparin1918

Tromexan1949

warfarin1950

phenindione1955

ticlopidine1975

clopidogrel1989

1918 Howell & Holt in Amer. Jrnl. Physiol. XLVII. 328 A phosphatid, not previously described, which exists in various tissues but is found in greatest abundance in the liver. This phosphatid is designated as heparin to indicate its origin from liver... This substance was [previously] described under the name of antiprothrombin.

1933 Jrnl. Biol. Chem. 102 435 Dog liver contains approximately twice as much heparin as does beef liver.

1946 Nature 24 Aug. 270/1 Even drastic blood changes brought about by the injection of dicoumarol or heparin had only a slight effect on the rate of growth of the bugs.

1968 A. White et al. Princ. Biochem. (ed. 4) xxxi. 732 Many tissues of the body contain heparin since it specifically originates in the metachromatic granules of mast cells.

Derivatives

ˌhepariniˈzation n. the process of heparinizing.

ΘΚΠ

the world > health and disease > healing > medical treatment > treatment by medicine or drug > [noun] > treatment with specific substances

mercurialization1825

cinchonization1875

helleborism1883

cocainization1887

tuberculinization1892

gold therapy1894

strychninization1898

venomization1905

strychnization1916

heparinization1956

reserpinization1959

1956 New Eng. Jrnl. Med. 29 Nov. 1027/2 General heparinization carries with it the risk of serious hemorrhage from bleeding lesions elsewhere in the body as well as at the operative site.

1961 Lancet 14 Oct. 858/1 The principle of regional heparinisation is to supply anticoagulated blood to the artificial kidney, whilst not interfering with the normal coagulation of blood in the patient.

ˈheparinize v. (transitive) to treat with heparin and thus reduce the clotting power of the blood.

ΚΠ

1959 Lancet 11 July 25/1 The risk of heparinising a patient who is receiving a coumarin drug.

ˈheparinized adj.

ΘΚΠ

the world > health and disease > healing > medical treatment > treatment by medicine or drug > [adjective] > treated with specific drugs

citrated1757

oxalated1893

mercurialized1897

insulinized1928

strychninized1938

heparinized1940

reserpinized1955

1940 J. E. R. McDonagh Universe through Med. 24 Snake venom has the same action in this condition as has calcium in making heparinised blood coagulate.

1943 Science 2 July 20/1 In all experiments in which heparinized whole blood or plasma was administered the lipemia was abolished.

This entry has not yet been fully updated (first published 1976; most recently modified version published online March 2022).

单词	heparin
释义	heparinn. Brit. /ˈhɛpərɪn/, U.S. /ˈhɛpərən/ Etymology: < hepar n. + -in suffix¹. Biochemistry. A sulphated polysaccharide present in various body tissues and organs, esp. the liver, lungs, and muscles, and used therapeutically as an anti-coagulant. ΘΚΠ the world > health and disease > healing > medicines or physic > medical preparations of specific origin > biological product > [noun] > specific lardc1420 sevumc1440 larding1582 protamine1874 renin1894 serum1895 sturine1896 iodothyrin1897 zymin1901 heparin1918 antireticular cytotoxic serum1942 urokinase1952 cryoprecipitate1956 xenoantiserum1973 anti-serum- the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations for treating specific parts > [noun] > for the blood > anti-coagulants anti-coagulant1905 heparin1918 Tromexan1949 warfarin1950 phenindione1955 ticlopidine1975 clopidogrel1989 1918 Howell & Holt in Amer. Jrnl. Physiol. XLVII. 328 A phosphatid, not previously described, which exists in various tissues but is found in greatest abundance in the liver. This phosphatid is designated as heparin to indicate its origin from liver... This substance was [previously] described under the name of antiprothrombin. 1933 Jrnl. Biol. Chem. 102 435 Dog liver contains approximately twice as much heparin as does beef liver. 1946 Nature 24 Aug. 270/1 Even drastic blood changes brought about by the injection of dicoumarol or heparin had only a slight effect on the rate of growth of the bugs. 1968 A. White et al. Princ. Biochem. (ed. 4) xxxi. 732 Many tissues of the body contain heparin since it specifically originates in the metachromatic granules of mast cells. Derivatives ˌhepariniˈzation n. the process of heparinizing. ΘΚΠ the world > health and disease > healing > medical treatment > treatment by medicine or drug > [noun] > treatment with specific substances mercurialization1825 cinchonization1875 helleborism1883 cocainization1887 tuberculinization1892 gold therapy1894 strychninization1898 venomization1905 strychnization1916 heparinization1956 reserpinization1959 1956 New Eng. Jrnl. Med. 29 Nov. 1027/2 General heparinization carries with it the risk of serious hemorrhage from bleeding lesions elsewhere in the body as well as at the operative site. 1961 Lancet 14 Oct. 858/1 The principle of regional heparinisation is to supply anticoagulated blood to the artificial kidney, whilst not interfering with the normal coagulation of blood in the patient. ˈheparinize v. (transitive) to treat with heparin and thus reduce the clotting power of the blood. ΚΠ 1959 Lancet 11 July 25/1 The risk of heparinising a patient who is receiving a coumarin drug. ˈheparinized adj. ΘΚΠ the world > health and disease > healing > medical treatment > treatment by medicine or drug > [adjective] > treated with specific drugs citrated1757 oxalated1893 mercurialized1897 insulinized1928 strychninized1938 heparinized1940 reserpinized1955 1940 J. E. R. McDonagh Universe through Med. 24 Snake venom has the same action in this condition as has calcium in making heparinised blood coagulate. 1943 Science 2 July 20/1 In all experiments in which heparinized whole blood or plasma was administered the lipemia was abolished. This entry has not yet been fully updated (first published 1976; most recently modified version published online March 2022). < n.1918
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