hepato-comb. form

1811 R. Hooper Quincy's Lexicon-medicum (new ed.) Hepatocele, an hernia in which a portion of the liver protrudes through the abdominal parietes.

1940 E. Rosenthal Dis. Digestive Syst. iii. 212 Jaundice may be i. Mechanical ii. Functional (hepato~cellular) iii. Hæmolytic.

1949 J. L. Kantor & A. M. Kasich Handbk. Digestive Dis. (ed. 2) xvii. 415 The hepato~cellular and the obstructive forms of jaundice make up more than 95 per cent of the cases encountered in clinical practice.

1962 Lancet 13 Jan. 67/1 Patients with hepato~cellular disease are faced with the prospect of hepatic coma and death every time they have a haemorrhage.

1739 C. Amyand in Philos. Trans. 1737–8 (Royal Soc.) 40 322 Hepaticystic Ducts.

1767 J. Hunter in Philos. Trans. 1766 (Royal Soc.) 56 309 The hepatocystic ducts..enter the gall-bladder at its anterior end or fundus.

1880 J. W. Legg On Bile 89 Schiff..tied all the structures in the hepato-duodenal ligament, save the hepatic artery.

1933 K. G. Stern in Nature 18 Nov. 784/1 The isolation in a crystalline state of the lyochrome from horse liver, to be designated as ‘hepatoflavin’, has been achieved.

1936 Jrnl. Nutrition 11 75 Fractions prepared from liver extract which were rich in vitamin G (B₂) and from which the hepatoflavin had been removed..were very active in the cure of black tongue.

1943 M. E. Rehfuss Indigestion xxiv. 392 The terms lactoflavin, ovoflavin, hepato~flavin, and so on serve to indicate the source of the particular riboflavin under discussion.

1960 A. E. Bender Dict. Nutrition & Food Technol. 62/1 Hepatoflavin, name given to substance isolated from liver, shown later to be riboflavin.

1876 J. Van Duyn & E. C. Seguin tr. E. L. Wagner Man. Gen. Pathol. 551 Hepatogenic Icterus in the duodenum.

1886 New Sydenham Soc. Lexicon Hepatogenic icterus, jaundice produced by the absorption of bile already formed in the liver.

1906 Practitioner Nov. 591 The most enthusiastic hepatogenists.

1875 H. C. Wood Treat. Therapeutics (1879) 109 That the icterus is not really hepatogenous, but haemic in origin.

1897 T. C. Allbutt et al. Syst. Med. II. 400 True hepatogenous jaundice, with bile pigment in the urine and decolouration of the fæces.

1922 Lancet 29 Apr. 849/2 This is an account of the disease known as progressive lenticular degeneration, which Dr. Hall christens hepato-lenticular degeneration.

1925 Brain 48 332 It would be better to adopt Hall's terminology, and refer to the condition as hepato~lenticular degeneration... This title fails to indicate the peculiar type of the disease in the liver..but it indicates..that the lenticular disease is a sequel to liver damage.

1945 Arch. Internal Med. 75 151/1 Wilson in 1912..first clearly defined the condition now most widely known as hepatolenticular degeneration.

1955 S. Sherlock Dis. Liver & Biliary Syst. xiii. 339 Hepatolenticular degeneration is a rare disease of young people characterised by portal cirrhosis of the liver, bilateral softening and degeneration of the lenticular nuclei of the basal ganglia of the brain, and greenish-brown pigmented rings in the periphery of the cornea.

1854 R. G. Mayne Expos. Lexicon Med. Sci. (1860) Hepatolithicus, of or belonging to a hepatolith, hepatolithic.

1888 Sci. Amer. LVIII. 98 Dr. Harley, the English hepatologist and nephrologist.

1903 Med. Rec. 18 July 84 A hepatolytic serum.

1893 R. J. Dunglison Dunglison's Dict. Med. Sci. (ed. 21) 524/1 Hepatomegalia.

1910 V. E. Collins & J. A. Liebmann tr. G. Dieulafoy Text-bk. Med. II. viii. i. 1916 He [sc. Glénard] found that hepatomegalia is the most frequent of the organic changes in diabetes.

1903 T. L. Stedman Dunglison's Dict. Med. Sci. (ed. 23) 527/1 Hepatomegaly, enlargement of the liver.

1937 J. L. Kantor Synopsis Digestive Dis. xxi. 230 Cancer of the liver must be differentiated from other conditions causing hepatomegaly.

1884 A. Sedgwick & F. G. Heathcote tr. C. Claus Elem. Text-bk. Zool.: Protozoa to Insecta 59 In the Invertebrata the secretions of many glands, which are generally called ‘liver’, but which would be more appropriately termed hepatopancreas.

1886 New Sydenham Soc. Lexicon Hepato-renal ligament, a reflection of the peritonæum extending from the transverse fissure of the liver to the kidney.

1947 W. H. Auden Age of Anxiety (1948) vi. 121 Peace was promised by the public hepatoscopists.

1728 E. Chambers Cycl. at Divination Hepatoscopy, or the Consideration of the Liver.

1928 C. Dawson Age of Gods xiii. 307 The practice of Hepatoscopy or divination from the liver of the sacrificial victim, which reached Asia Minor from Mesopotamia, was carried by the Etruscans to Italy.

1957 Encycl. Brit. XI. 451/1 The theory underlying hepatoscopy consists of the belief (1) that the liver is the seat of life, or the soul of the animal; and (2) that the liver of the sacrificial animal..took on the same character as the soul of the god to whom it was offered.

1930 Chem. Abstr. 24 886 In hepatosplenomegalia and hepatic cirrhosis, the urobilin increased in the urine and feces.

1939 T. L. Stedman & S. T. Garber Pract. Med. Dict. (ed. 14) 496/2 Hepatosplenomegaly.

1961 Lancet 19 Aug. 434/2 Physical examination revealed considerable hepatosplenomegaly.

1940 Jrnl. Amer. Med. Assoc. 28 Dec. 2264/2 (heading) Alleged hepatotoxic action of stilbestrol.

1961 Lancet 16 Sept. 623/1 Each of the drugs which has caused jaundice is a derivative of hydrazine, itself a potent hepatotoxic agent in laboratory animals.

1972 Nature 4 Feb. 279/1 Both compounds..have been reported to be hepatotoxic, carcinogenic, teratogenic and neurotoxic.

1952 New Eng. Jrnl. Med. 20 Nov. 797 (heading) The hepatotoxicity of intravenous aureomycin.

1969 Nature 19 Apr. 223/2 Increase in size of the liver (hepatomegaly) is not a reliable indication of hepatotoxicity.

1903 T. L. Stedman Dunglison's Dict. Med. Sci. (ed. 23) 527/1 Hepatotoxin, a cytotoxin having a specific action on the cells of the liver.

1909 J. G. Adami Princ. Pathol. I. iii. viii. 489 Ciliated epithelium was shown to have its cytotoxin.., as have kidney cells (nephrotoxin), liver cells (hepatotoxin), pancreatic, adrenal, in fact, every form of animal cell that has been tested.

1929 Chem. Abstr. 23 5509 Hepatotoxins, prepd. by immunizing rabbits with emulsions of rabbit and rat livers, were injected into rabbits and rats.

1951 A. Grollman Pharmacol. & Therapeutics xxvii. 607 Because of their lipotropic action, choline and, to a lesser extent, methionine..have been used therapeutically in cirrhosis of the liver,..and as a prophylactic in poisoning by hepatotoxins.

1963 G. Klatskin in L. Schiff Dis. Liver (ed. 2) xiv. 453/1 Hepatotoxins, a heterogeneous group of naturally occurring and synthetic chemical agents, produce a variety of lesions in the liver that are classified as forms of toxic hepatitis.