单词 | histamine |
释义 | histaminen. Biochemistry and Medicine. A biologically active amine present in animal and plant tissues and stored in the granules of mast cells and basophils, serving esp. as a vasodilator, a regulator of gastric secretion and capillary permeability, and a mediator of allergic reactions.Histamine is derived from histidine by decarboxylation.Systematic name: 2-(4-imidazolyl)ethylamine; C5H9N3. ΘΚΠ the world > matter > chemistry > organic chemistry > amines > [noun] > named ethylamine1849 amylamine1850 ethylia1850 petinine1850 triethylamine1850 polyamine1861 nonylamine1866 octylamine1866 carbylamine1868 tetrylamine1868 hydroxylamine1871 hydramine1877 nitrosamine1878 guanamine1881 hexamethylenetetramine1888 morpholine1889 triethanolamine1897 tropane1898 agmatine1910 tyramine1910 histamine1912 spermidine1927 monoethanolamine1929 tryptamine1929 octopamine1948 norsynephrine1952 tilorone1970 1912 Therapeutic Gaz. 15 Dec. 878/1 Certain peculiarities in its behavior..suggested to him [sc. Fühner] a connection between pituitrin and B-imidazolylethylamin (histamin),..and..he recommends a trial of histamin in obstetrical clinics. 1920 Nature 4 Mar. 11/2 A compound of known chemical structure, called ‘histamine’,..which is able to produce a state of the circulation like that present in wound-shock. 1929 Times 28 Oct. 15/3 These products produce what is spoken of as ‘histamine poisoning’, the substance histamine being the principal toxic agent. 1957 New Biol. 24 54 Histamine belongs to a group of substances known chemically as amines and physiologically as vasodilators, i.e. they dilate the blood vessels. 2002 Frederick (Maryland) News-Post 7 Oct. b12/1 Most cases of hives are caused by the release of histamine into the skin from an allergic reaction. Derivatives ˌhistaˈminic n. of, relating to, or caused by histamine. ΚΠ 1937 Rev. Gastroenterol. 4 281 Many authors..have established the possibility of a person becoming sensitized by this compound [sc. histamine], it being possible to provide a histaminic shock, in much the same way as that of an anaphylactic shock. 1963 Lancet 19 Jan. 129/1 When trimetaphan is used, its powerful histaminic action may be dangerously potentiated by the presence of complete adrenergic blockade. 2001 D. E. Smith & R. Seymour Clinician’s Guide Substance Abuse 89 Runny nose can also result from histaminic discharges in heroin use. This entry has been updated (OED Third Edition, March 2012; most recently modified version published online March 2022). < n.1912 |
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