histonen.

Brit.

/ˈhɪstəʊn/, U.S.

/ˈhɪˌstoʊn/

Forms: 1800s– histon, 1800s– histone.

Origin: Formed within English, by derivation; modelled on a German lexical item. Etymons: histo- comb. form, -one suffix.

Etymology: < histo- comb. form + -one suffix, after German Histon (A. Kossel 1884, in Zeitschr. f. physiol. Chem. 8 512).

Biochemistry and Molecular Biology.

Any of a class of small basic proteins which are found in association with DNA in chromatin, and play an important role in the regulation of gene activity.

ΘΚΠ

the world > life > biology > substance > proteins > [noun]

casein1838

albuminoid1855

xanthoglobulin1868

myochrome1872

xanthoprotein1883

histone1885

globulose1886

phaseolin1893

leucosin1894

nucleohistone1894

nucleon1895

mucoid1898

protone1898

mucinoid1902

myohaemoglobin1906

nucleoprotamine1911

cytozyme1914

leaf protein1917

cytochrome1925

mucoprotein1925

myoglobin1925

flavoprotein1934

oxymyoglobin1935

ferritin1937

lipovitellin1942

arthropodin1947

trypticase1947

erythropoietin1948

phosvitin1948

opsin1951

orosomucoid1955

metallothionein1960

plastocyanin1961

aequorin1962

ferredoxin1962

LDL1962

fetoprotein1964

thioredoxin1964

actinin1965

adrenodoxin1965

lactoferrin1965

myoglobulin1965

rubredoxin1965

uniporter1967

miraculin1968

nexin1970

bacteriorhodopsin1971

molybdoprotein1971

monellin1972

cytokine1974

ankyrin1975

clathrin1975

electromorph1975

tau1975

uniport1975

microtrabecula1976

porin1976

osteocalcin1977

calmodulin1978

monokine1978

PCNA1978

vimentin1978

interleukin1979

laminin1979

titin1979

villin1979

cyclin1981

triskele1981

acumentin1982

perforin1983

statin1985

activin1986

addressin1988

synuclein1988

chemokine1992

1885 Jrnl. Chem. Soc. 48 i. 572 Extraction with dilute acid isolates a substance which belongs to the class of bodies called A-peptones by Meissner... The author [sc. Kossel] names this substance histon.

1899 Jrnl. Chem. Soc. 76 836 Next Lilienfeld separated from the thymus, spleen, and testis a histone combined with nuclein (nucleo-histone).

1952 Sci. News 24 37 Histones..are present in appreciable amounts in the nuclei of the tissue cells of all animal species examined.

1968 New Scientist 7 Nov. 319/3 What now seems much more possible is that the histones are simply the tool needed to shut down genes, and that they are instructed which particular gene..to shut down by another, specific, molecule.

2004 Toronto Star 26 Nov. c5/1 A double helix DNA strand winds around a histone protein core to make a structure called a nucleosome.

This entry has been updated (OED Third Edition, March 2012; most recently modified version published online March 2022).

单词	histone
释义	histonen. Brit. /ˈhɪstəʊn/, U.S. /ˈhɪˌstoʊn/ Forms: 1800s– histon, 1800s– histone. Origin: Formed within English, by derivation; modelled on a German lexical item. Etymons: histo- comb. form, -one suffix. Etymology: < histo- comb. form + -one suffix, after German Histon (A. Kossel 1884, in Zeitschr. f. physiol. Chem. 8 512). Biochemistry and Molecular Biology. Any of a class of small basic proteins which are found in association with DNA in chromatin, and play an important role in the regulation of gene activity. ΘΚΠ the world > life > biology > substance > proteins > [noun] casein1838 albuminoid1855 xanthoglobulin1868 myochrome1872 xanthoprotein1883 histone1885 globulose1886 phaseolin1893 leucosin1894 nucleohistone1894 nucleon1895 mucoid1898 protone1898 mucinoid1902 myohaemoglobin1906 nucleoprotamine1911 cytozyme1914 leaf protein1917 cytochrome1925 mucoprotein1925 myoglobin1925 flavoprotein1934 oxymyoglobin1935 ferritin1937 lipovitellin1942 arthropodin1947 trypticase1947 erythropoietin1948 phosvitin1948 opsin1951 orosomucoid1955 metallothionein1960 plastocyanin1961 aequorin1962 ferredoxin1962 LDL1962 fetoprotein1964 thioredoxin1964 actinin1965 adrenodoxin1965 lactoferrin1965 myoglobulin1965 rubredoxin1965 uniporter1967 miraculin1968 nexin1970 bacteriorhodopsin1971 molybdoprotein1971 monellin1972 cytokine1974 ankyrin1975 clathrin1975 electromorph1975 tau1975 uniport1975 microtrabecula1976 porin1976 osteocalcin1977 calmodulin1978 monokine1978 PCNA1978 vimentin1978 interleukin1979 laminin1979 titin1979 villin1979 cyclin1981 triskele1981 acumentin1982 perforin1983 statin1985 activin1986 addressin1988 synuclein1988 chemokine1992 1885 Jrnl. Chem. Soc. 48 i. 572 Extraction with dilute acid isolates a substance which belongs to the class of bodies called A-peptones by Meissner... The author [sc. Kossel] names this substance histon. 1899 Jrnl. Chem. Soc. 76 836 Next Lilienfeld separated from the thymus, spleen, and testis a histone combined with nuclein (nucleo-histone). 1952 Sci. News 24 37 Histones..are present in appreciable amounts in the nuclei of the tissue cells of all animal species examined. 1968 New Scientist 7 Nov. 319/3 What now seems much more possible is that the histones are simply the tool needed to shut down genes, and that they are instructed which particular gene..to shut down by another, specific, molecule. 2004 Toronto Star 26 Nov. c5/1 A double helix DNA strand winds around a histone protein core to make a structure called a nucleosome. This entry has been updated (OED Third Edition, March 2012; most recently modified version published online March 2022). < n.1885
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