homeodomainn.

Brit.

/ˈhəʊmɪə(ʊ)də(ʊ)ˌmeɪn/, U.S.

/ˈhoʊmiədoʊˈˌmeɪn/,

/ˈhoʊmiədəˈˌmeɪn/

Forms: 1900s– homeodomain (British), 1900s– homoeodomain (British).

Origin: Formed within English, by compounding. Etymons: homoeo- comb. form, domain n.

Etymology: < homoeo- comb. form + domain n.

Genetics and Molecular Biology.

A sequence of 60 amino acids encoded by a homeobox, forming a distinctive structural domain with a DNA-binding function in proteins involved in the regulation of transcription and (less commonly) translation.

ΚΠ

1984 Cell 37 412/1 The Xenopus conserved domain and the three Drosophila homeo domains might serve the same function.

1988 Nature 22–9 Dec. 744/1 A combination of segmentation and homoeotic gene products, many of which contain homoeodomains, specify the developmental fates of cells in striped patterns.

2007 B. Glover Understanding Flowers iv. 41 The LD gene..encodes a homeodomain protein, a structure usually associated with DNA binding and transcriptional regulation.

This entry has been updated (OED Third Edition, September 2011; most recently modified version published online March 2022).

单词	homeodomain
释义	homeodomainn. Brit. /ˈhəʊmɪə(ʊ)də(ʊ)ˌmeɪn/, U.S. /ˈhoʊmiədoʊˈˌmeɪn/, /ˈhoʊmiədəˈˌmeɪn/ Forms: 1900s– homeodomain (British), 1900s– homoeodomain (British). Origin: Formed within English, by compounding. Etymons: homoeo- comb. form, domain n. Etymology: < homoeo- comb. form + domain n. Genetics and Molecular Biology. A sequence of 60 amino acids encoded by a homeobox, forming a distinctive structural domain with a DNA-binding function in proteins involved in the regulation of transcription and (less commonly) translation. ΚΠ 1984 Cell 37 412/1 The Xenopus conserved domain and the three Drosophila homeo domains might serve the same function. 1988 Nature 22–9 Dec. 744/1 A combination of segmentation and homoeotic gene products, many of which contain homoeodomains, specify the developmental fates of cells in striped patterns. 2007 B. Glover Understanding Flowers iv. 41 The LD gene..encodes a homeodomain protein, a structure usually associated with DNA binding and transcriptional regulation. This entry has been updated (OED Third Edition, September 2011; most recently modified version published online March 2022). < n.1984
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