hyaluronidasen.
/ˌhʌɪəljʊˈrɒnɪdeɪz//ˌhʌɪəljʊˈrɒnɪdeɪs/ Biochemistry.
Any of the enzymes which catalyse the depolymerization of hyaluronic acid, thereby reducing its viscosity and rendering tissue containing it more permeable.
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the world > life > biology > biological processes > genetic activity > genetic components > [noun] > nucleic acid > enzymes
galactase1898
cellulase1901
nuclease1902
xanthine oxidase1905
exoenzyme1908
glucosidase1909
galactase1910
nucleosidase1911
nucleotidase1911
adenosine deaminase1913
cellobiase1919
hydratase1922
activase1928
hexokinase1930
histaminase1930
kallikrein1930
Michaelis constant1930
cholinesterase1932
phosphodiesterase1932
chymotrypsin1933
glycosidase1933
rhodanese1933
acetylcholinesterase1937
prolidase1937
diaphorase1938
aconitase1939
hyaluronidase1940
transaminase1940
hydrase1943
isomerase1943
lactoperoxidase1943
streptokinase1944
pectinesterase1945
pectinmethylesterase1945
phosphokinase1946
alliinase1947
CoA1947
phosphotransferase1948
polymerase1948
transferase1948
elastase1949
amyloglucosidase1950
transacetylase1950
transhydrogenase1952
hydroxylase1953
kinase1953
transketolase1953
synthase1954
hexosaminidase1955
translocase1957
angiotensinase1958
angiotensin converting enzyme1960
photoenzyme1960
acetyltransferase1961
adenyl cyclase1961
adenylate cyclase1962
replicase1962
ADA1963
transcriptase1963
adenylyl cyclase1964
recombinase1964
laminarinase1966
nickase1967
acrosin1970
reverse transcriptase1970
cellobiohydrolase1972
cyclooxygenase1974
laminaranase1974
primase1977
helicase1978
monodeiodinase1978
transposase1979
maturase1980
1940 Chain & Duthie in Brit. Jrnl. Exper. Path. XXI. 325 Hyaluronic acid is the substrate for the ‘mucolytic’ enzyme in spreading factor solution which accordingly is termed ‘hyaluronidase’.
1951 A. Grollman Pharmacol. & Therapeutics xxix. 652 To accelerate the rate of absorption from the skin and subcutaneous tissues, hyaluronidase may be added to the infusion.
1967 Martindale's Extra Pharmacopoeia (ed. 25) 886/1 The diffusion of local anaesthetics is accelerated by the addition of 1000 units of hyaluronidase to each 20 ml. of the anaesthetic solution.
1970 E. J. Ambrose & D. M. Easty Cell Biol. xii. 391 The sperm acrosome secretes enzymes (including hyaluronidase) which assist penetration [of the ovum].
This entry has not yet been fully updated (first published 1976; most recently modified version published online September 2018).
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n.1940