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hyposplenism
hyposplenism n. 
/ˌhʌɪpə(ʊ)ˈsplɛnɪz(ə)m/, /ˌhaɪpəˈsplɛˌnɪzəm/, /ˌhaɪpoʊˈspliˌnɪzəm/, /ˌhaɪpoʊˈsplɛˌnɪzəm/ [ < German Hyposplenie (H. Eppinger 1913, in Berliner Klin. Wochenschr. Latin 1509/2)] Pathology an abnormally low rate of activity of the spleen, esp. as regards the repair of damaged red blood cells.
Brit. /ˌhʌɪpə(ʊ)ˈspliːnɪz(ə)m/
, /ˌhʌɪpə(ʊ)ˈspliːnɪz(ə)m//ˌhʌɪpə(ʊ)ˈsplɛnɪz(ə)m/U.S. /ˌhaɪpəˈspliˌnɪzəm/
, /ˌhaɪpəˈspliˌnɪzəm//ˌhaɪpəˈsplɛˌnɪzəm//ˌhaɪpoʊˈspliˌnɪzəm//ˌhaɪpoʊˈsplɛˌnɪzəm/ΘΚΠ
the world > health and disease > ill health > a disease > disorders of internal organs > glandular disorders > [noun] > disorders of spleen
elf-cake1579
ague cake1597
splenitis1753
lienitis1845
perisplenitis1881
wandering spleen1897
splenohepatomegaly1900
spleno-megaly1900
hypersplenism1914
hyposplenism1914
splenosis1939
1914 Arch. Internal Med. 14 145 A condition of decreased function [of the spleen] may be conceived to be within the range of organ activity, a state of hyposplenism.
1966 J. W. Linman Princ. Hematol. xii. 449 The hematologic effects of splenectomy are definite and provide insight into the functions of the normal spleen. All blood cells are affected by ‘hyposplenism’.
1987 D. J. Weatherall et al. Oxf. Textbk. Med. (ed. 2) II. xix. 245/1 The peripheral blood changes of hyposplenism are quite frequently associated with an underlying malabsorption syndrome.
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