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单词 aromatase
释义

aromatasen.

Brit. /əˈrəʊməteɪz/, U.S. /əˈroʊməˌteɪz/, /əˈroʊməˌteɪs/
Origin: Formed within English, by derivation. Etymons: aromatization n., aromatize v., -ase suffix.
Etymology: < aromat- (in either aromatization n. or aromatize v.) + -ase suffix.
Biochemistry.
An enzyme that catalyses an aromatization reaction; spec. one that converts androgens to oestrogens by aromatization.
ΚΠ
1959 Biochimica et Biophysica Acta 36 103 (caption) ‘Prephenic aromatase’ has been suggested (personal communication from Dr. B. D. Davis) as the name for the enzyme aromatizing PPA [= prephenic acid] to phenylpyruvate.
1973 Amer. Jrnl. Obstetr. & Gynecol. 117 345 (title) Evaluation of placental steroid 3-sulfatase and aromatase activities as regulators of estrogen production in human pregnancy.
1983 N. G. Simon in E. C. Simnel et al. Aggressive Behavior ii. 20 (caption) Testosterone is enzymatically converted to estradiol by aromatase.
2004 J. Ogden Understanding Breast Cancer xii. 102 Aromatase inhibitors such as anastrozole (Arimidex)..and have been shown to be even more effective than tamoxifen in cutting the risk of cancer recurring in oestrogen-positive cancers.
This is a new entry (OED Third Edition, June 2007; most recently modified version published online December 2021).
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n.1959
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