单词 | hyperchromatosis |
释义 | hyperchromatosisn. 1. Medicine. Excessive colouring or pigmentation, esp. of the skin. ΘΚΠ the world > health and disease > ill health > a disease > disorders of visible parts > skin disorders > [noun] > disordered pigmentation melasma1563 orange skin1822 melanopathia1847 xanthosis1853 xanthelasma1867 xanthochroia1867 xanthoderma1867 xanthopathia1867 xanthoma1869 argyria1874 chloasma1877 leucoderma1884 xeroderma pigmentosum1884 hyperchromatosis1886 melanodermia1886 leucodermia1888 hyperchromasia1889 hyperpigmentation1890 hypochromia1890 xanthochromia1894 xanthodermia1900 melanization1927 1886 New Sydenham Soc. Lexicon Hyperchromatosis, Auspitz's term for an excessive deposit of pigment in the epidermis. 1919 Encycl. Medica (ed. 2) VI. 272 Hyperchromatosis, excessive pigmentation, especially in certain skin diseases. 2. Cytology. [ < German hyperchromatose (R. Woltereck 1898, in Zeitschr. f. wiss. Zool. LXIV. 604).] An abnormally large number of chromosomes or amount of chromatin in a cell or nucleus. ΘΚΠ the world > life > biology > biological processes > genetic activity > genetic components > [noun] > chromatin > state of hyperchromatosis1898 chromaticity1904 hypochromatosis1913 hyperchromasia1930 1898 Jrnl. Royal Microsc. Soc. 628 They are remarkable for their excess of chromosomes (hyperchromatosis), and for the tendency these have to group themselves in dyads and tetrads. 1913 J. Ritchie in Pembrey & Ritchie Text-bk. Gen. Path. viii. 240 In malignant tumours the division of the chromosomes between the poles is often unequal... This can be recognized by the existence of differences in size and staining qualities of the nuclei, and the two phenomena are sometimes referred to as hyperchromatosis and hypochromatosis. 1946 Nature 31 Aug. 304/1 A hyperchromatosis and pyknosis of the nucleus which has hitherto been wrongly interpreted as a degeneration. This entry has not yet been fully updated (first published 1976; most recently modified version published online June 2018). < n.1886 |
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