immunosorbentn.adj.
/ˌɪmjᵿnəʊˈzɔːb(ə)nt/, /ˌɪmjᵿnəʊˈsɔːb(ə)nt/, /ɪˌmjuːnəʊˈzɔːb(ə)nt/, /ɪˌmjuːnəʊˈsɔːb(ə)nt/, U.S. /ˌɪmjənoʊˈzɔrb(ə)nt/, /ˌɪmjənoʊˈsɔrb(ə)nt/, /ᵻˌmjunoʊˈzɔrb(ə)nt/, /ᵻˌmjunoʊˈsɔrb(ə)nt/ Medicine and Biology.
A. n.
A solid matrix on to which specific antibody or antigen is adsorbed, used to capture the corresponding antigen or antibody from solution.
ΚΠ
1961 A. E. Gourvich et al. in Biokhimiia 26 942 (heading) Production of protein-cellulose complexes (immunosorbents) in the form of suspensions able to bind great amounts of antibodies.
1988 A. M. Silverstein Hist. Immunol. vii. 183 Where a receptor-specific autoantibody can be identified as the cause of a disease, its (temporary) alleviation may be obtained..by removing the antibody by means of plasmapheresis or perhaps, eventually, specific immunosorbents.
2001 New Scientist 9 June (Graduate Careers Suppl.) 21/1 Synthesis and characterisation of carbon-based immunosorbents for extracorporeal blood perfusion.
B. adj.
Designating or relating to laboratory techniques that use an immunosorbent, esp. in enzyme-linked immunosorbent assay (cf. ELISA n.).
ΚΠ
1965 Jrnl. Lab. & Clin. Med. 66 682 (title) Use of an immunosorbent technique in the study of a PTC inhibitor.
1983 Molecular & Cell. Biol. 3 1343 Its [sc. the antibody] interaction with phosphotyrosyl proteins is sensitive to ionic detergents and to antibody density on the immunosorbent matrix.
2001 Indiaweekly 16 Mar. 43/5 For the sero-surveillance program, the presence of antibodies to HIV antigens in the test sample of blood or plasma is ascertained by the Enzyme Linked Immunosorbent Assay (Elisa) test.
This is a new entry (OED Third Edition, June 2008; most recently modified version published online March 2022).
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n.adj.1961