inactivatorn.
/ɪnˈaktɪveɪtə/, U.S. /ᵻnˈæktəˌveɪdər/ 1. An agent that inactivates something.
ΘΚΠ
the world > life > biology > biological processes > metabolism > [noun] > that which metabolises or inactivates
inactivator1905
1905 Amer. Jrnl. Physiol. 13 187 The injection of calcium precipitants and ‘inactivators’ in the form of sodium salts, into the..circulation of the frog, sets up fibrillary twitchings of the whole musculature.
1946 Nature 10 Aug. 201/1 The inactivator or inactivators involved are susceptible to heat and do not pass through a Seitz filter.
2010 D. L. Purisch Enzyme Kinetics ii. 54 An irreversible inactivator is attached to an enzyme.
2. With distinguishing word. An individual who metabolizes and inactivates a drug, spec. the antibiotic isoniazid, at the specified rate. Cf. metabolizer n.
ΘΚΠ
the world > health and disease > healing > patient > [noun] > others
private patient1754
panel patient1913
mental patient1916
inactivator1957
responaut1964
gomer1972
1957 R. S. Mitchell & J. C. Bell in New Eng. Jrnl. Med. 28 Nov. 1069/1 Patients with levels this high or higher are classified as ‘slow inactivators’ of isoniazid.
1960 Times 11 Nov. 17/2 Individuals could be divided into two categories: rapid and slow inactivators of the drug.
1989 Pharmacol. & Therapeutics 42 157 Patients could be classified as ‘slow’ (about 60% of the population), ‘rapid’, (25%), and ‘intermediate’ inactivators of isoniazid.
2010 L. B. Jorde et al. Med. Genetics (ed. 4) xiv. 286/2 Persons who are homozygous for this allele are known as slow inactivators.
This entry has been updated (OED Third Edition, September 2021; most recently modified version published online March 2022).
<
n.1905