isotretinoinn.
/ˌʌɪsə(ʊ)trəˈtɪnəʊɪn/, U.S. /ˌaɪsoʊtrəˈtɪnəwən/ Pharmacology.
A synthetic isomer of tretinoin used in topical and oral forms in the treatment of severe acne.Isotretinoin is 13-cis-retinoic acid. It is a known teratogen.A proprietary name for this drug is Ro-accutane.
ΚΠ
1979 Jrnl. Amer. Med. Assoc. 5 Jan. 65/1 Isotretinoin..prophylactic and therapeutic agent for epithelial tissue dysplasia.
1987 Developmental Biol. 123 276 Isotretinoin (13-cis-retinoic acid), an anti-acne medication, has been found to cause severe birth defects.
2012 Sunday Tel. (Nexis) 22 July 19 If severe acne remains stubborn, then a course of isotretinoin tablets..is very often successful.
This is a new entry (OED Third Edition, March 2013; most recently modified version published online March 2022).
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n.1979