kernicterusn.

/kəːˈnɪktərəs/

Forms: Formerly also kern-, Kernikterus.

Etymology: < German kernikterus (G. Schmorl 1903, in Verhandl. d. Deut. Path. Ges. VI. 112), < kern nucleus + ikterus icterus n., jaundice.

Pathology.

The staining of nuclei of the brain cells with bilirubin, which sometimes occurs, usually associated with rhesus incompatibility, in neonatal jaundice, and which causes permanent brain damage; the disease or condition characterized by or associated with such staining.

ΘΚΠ

the world > health and disease > ill health > a disease > disorders of internal organs > disorders of nervous system > [noun] > disorders of brain > other brain disorders

brain damage1864

mind-blindness1888

satellitosis1906

syringobulbia1908

Alzheimer's disease1911

kernicterus1912

pseudotumour1914

brain death1928

punch-drunk1928

Sturge–Weber syndrome1935

Alzheimer1938

Creutzfeldt–Jakob1939

Alzheimer1940

Schilder's disease1940

hypsarrhythmia1952

kuru1957

laughing death1957

Minamata disease1957

myelinolysis1959

spongiform encephalopathy1960

CJD1975

old-timer's disease1983

mad —— disease1990

1912 Brain 34 488 An important analogy may be drawn from the occurrence of ‘Kernikterus’ in certain cases of familial icterus gravis neonatorum.

1933 Amer. Jrnl. Dis. Children 45 757 Opinion is almost unanimous on the subject of the pathogenesis of kernikterus, namely, that following some injury, the nerve cells are subsequently stained with the bile pigments carried to them by the blood stream.

1950 Jrnl. Laryngol. & Otol. 64 505 Sixteen cases of perceptive deafness associated with kernicterus are reported. In fourteen of these cases the jaundice was due to Rh iso-immunization.

1953 Lancet 28 Mar. 613/1 Kernicterus is never found apart from jaundice.

1965 Amer. Jrnl. Pathol. 46 336 Yellow ganglion and glial cells, characteristic features of human kernicterus, were demonstrated in 23 rabbits.

Derivatives

kerˈnicteric adj. afflicted or associated with kernicterus.

ΘΚΠ

the world > health and disease > ill health > a disease > disorders of internal organs > disorders of nervous system > [adjective] > disorders of brain > other brain disorders

hardbound?a1425

bound1704

Wernicke1887

mind-blind1905

Alzheimer1911

Waterhouse–Friderichsen syndrome1934

brain-damaged1946

kernicteric1956

brain-dead1972

C-J1972

hypsarrhythmic1977

flatline1978

Creutzfeldt–Jakob1987

1956 Jrnl. Speech & Hearing Disorders 21 407 (heading) Clinical pathologic aspects of kernicteric nuclear ‘deafness’.

1967 Jrnl. Neurochem. 14 192 The kernicteric animals are known to have pathologic lesions in the CNS comparable to those found in brain tissue of infants dying with kernicterus.

This entry has not yet been fully updated (first published 1976; most recently modified version published online June 2021).

单词	kernicterus
释义	kernicterusn. /kəːˈnɪktərəs/ Forms: Formerly also kern-, Kernikterus. Etymology: < German kernikterus (G. Schmorl 1903, in Verhandl. d. Deut. Path. Ges. VI. 112), < kern nucleus + ikterus icterus n., jaundice. Pathology. The staining of nuclei of the brain cells with bilirubin, which sometimes occurs, usually associated with rhesus incompatibility, in neonatal jaundice, and which causes permanent brain damage; the disease or condition characterized by or associated with such staining. ΘΚΠ the world > health and disease > ill health > a disease > disorders of internal organs > disorders of nervous system > [noun] > disorders of brain > other brain disorders brain damage1864 mind-blindness1888 satellitosis1906 syringobulbia1908 Alzheimer's disease1911 kernicterus1912 pseudotumour1914 brain death1928 punch-drunk1928 Sturge–Weber syndrome1935 Alzheimer1938 Creutzfeldt–Jakob1939 Alzheimer1940 Schilder's disease1940 hypsarrhythmia1952 kuru1957 laughing death1957 Minamata disease1957 myelinolysis1959 spongiform encephalopathy1960 CJD1975 old-timer's disease1983 mad —— disease1990 1912 Brain 34 488 An important analogy may be drawn from the occurrence of ‘Kernikterus’ in certain cases of familial icterus gravis neonatorum. 1933 Amer. Jrnl. Dis. Children 45 757 Opinion is almost unanimous on the subject of the pathogenesis of kernikterus, namely, that following some injury, the nerve cells are subsequently stained with the bile pigments carried to them by the blood stream. 1950 Jrnl. Laryngol. & Otol. 64 505 Sixteen cases of perceptive deafness associated with kernicterus are reported. In fourteen of these cases the jaundice was due to Rh iso-immunization. 1953 Lancet 28 Mar. 613/1 Kernicterus is never found apart from jaundice. 1965 Amer. Jrnl. Pathol. 46 336 Yellow ganglion and glial cells, characteristic features of human kernicterus, were demonstrated in 23 rabbits. Derivatives kerˈnicteric adj. afflicted or associated with kernicterus. ΘΚΠ the world > health and disease > ill health > a disease > disorders of internal organs > disorders of nervous system > [adjective] > disorders of brain > other brain disorders hardbound?a1425 bound1704 Wernicke1887 mind-blind1905 Alzheimer1911 Waterhouse–Friderichsen syndrome1934 brain-damaged1946 kernicteric1956 brain-dead1972 C-J1972 hypsarrhythmic1977 flatline1978 Creutzfeldt–Jakob1987 1956 Jrnl. Speech & Hearing Disorders 21 407 (heading) Clinical pathologic aspects of kernicteric nuclear ‘deafness’. 1967 Jrnl. Neurochem. 14 192 The kernicteric animals are known to have pathologic lesions in the CNS comparable to those found in brain tissue of infants dying with kernicterus. This entry has not yet been fully updated (first published 1976; most recently modified version published online June 2021). < n.1912
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