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单词 autophosphorylation
释义

autophosphorylationn.

Brit. /ˌɔːtə(ʊ)ˌfɒsfɒrᵻˈleɪʃn/, U.S. /ˌɔdoʊfɑsˌfɔrəˈleɪʃ(ə)n/, /ˌɑdoʊfɑsˌfɔrəˈleɪʃ(ə)n/
Origin: Formed within English, by compounding. Etymons: auto- comb. form1, phosphorylation n.
Etymology: < auto- comb. form1 + phosphorylation n.
Biochemistry.
Phosphorylation of a protein molecule which is catalysed by the kinase activity of the protein molecule itself.
ΚΠ
1972 FEBS Lett. 26 351/1 Fig. 3 shows the kinetics of autophosphorylation of brain (A) and thyroid (B) purified tubulin incubated with [γ-32P] ATP.
1989 J. Espinal Understanding Insulin Action v. 93 The autophosphorylation of the insulin receptor has been reported to occur in many tissues and cell types.
2006 Science 28 Apr. 572/3 In cells undergoing ER stress, BiP preferentially binds to misfolded proteins, thereby releasing the stress sensors to undergo activation by homodimerization and autophosphorylation.
This is a new entry (OED Third Edition, June 2011; most recently modified version published online December 2021).
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n.1972
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更新时间:2024/12/23 20:52:35