levallorphann.
/ˌliːvəˈlɔːfan/ Pharmacology.
A morphine analogue and opioid antagonist, C19H25NO, given intravenously (usually as the tartrate) to counteract some of the depressant effects of certain narcotics.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > medicine for mental conditions > [noun] > antidepressant > specific drugs
Marsilid1952
iproniazid1953
levallorphan1953
imipramine1958
Tofranil1958
isocarboxazid1959
Marplan1959
Nardil1959
nialamide1959
Niamid1959
phenelzine1959
tranylcypromine1959
Parnate1960
amitriptyline1961
monoamine oxidase inhibitor1962
nortriptyline1962
protriptyline1963
MAOI1965
maprotiline1970
mianserin1970
amoxapine1971
fluoxetine1975
paroxetine1977
Prozac1985
Seroxat1985
1953 Anesthesiology 14 550 Levallorphan is the generic name of 3-hydroxy-N-allylmorphan and was originally designated as R0 1-7700.
1977 Drug Metabolism & Disposition V. 273 Narcotic antagonists, naloxone, nalorphine, levallorphan, and naltrexone, specifically inhibited morphine glucuronidation.
1988 Biol. Abstr. 85 xi. ab929/1 Neuroleptanalgesia was performed by intravenous injection of fentanyl and levallorphan 5 minutes before local anesthesia.
1989 Martindale's Extra Pharmacopoeia (ed. 29) 84 2/2 Levallorphan reverses severe opioid-induced respiratory depression but may exacerbate respiratory such as that induced by alcohol or other non-opioid central depressants.
This entry has not yet been fully updated (first published 1997; most recently modified version published online June 2018).
<
n.1953