lipotropinn.
/lɪpə(ʊ)ˈtrəʊpɪn/ Biochemistry.
A polypeptide secreted by the pituitary gland which promotes the removal of fat from adipose tissue and stimulates the production of melanin. Usually with qualifying prefix or suffix to denote either the entire lipotropin molecule ( β-lipotropin or β-LPH) or any of several fragments.
ΚΠ
1964 New Scientist 23 Apr. 234/1 Another hormone has been added to the list of those secreted by the anterior lobe of the pituitary gland. It has been called lipotropin..because of its ability to dissolve fat pads removed from rabbits and rats.
1980 Nature 23 Oct. 752/2 The pituitary hormones corticotropin (ACTH) and β-lipotropin (β-LPH) are formed from a large common precursor.
1982 H. M. van Praag et al. in M. Motta et al. Pituitary Hormones & Related Peptides xxiii. 337 The amino acid sequence of the principal endorphins so far identified..lies embedded in β-lipotrophin (β-LPH), a hypophyseal hormone which comprises 91 amino acids.
1985 M. Wallis et al. Biochem. Polypeptide Hormones v. 108 Three lipotropins were first isolated from sheep anterior pituitary glands (α, β, and γ) and were subsequently also found and characterized in various other species, including man.
This entry has not yet been fully updated (first published 1993; most recently modified version published online December 2020).
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