macrophagen.

Brit.

/ˈmakrə(ʊ)feɪdʒ/, U.S.

/ˈmækrəˌfeɪdʒ/

Origin: Formed within English, by compounding; modelled on a German lexical item. Etymons: macro- comb. form, -phage comb. form.

Etymology: < macro- comb. form + -phage comb. form, after German Makrophagen (plural; E. Metschnikoff 1887, in Arch. f. Pathol. Anat. u. Physiol. 107 222). Compare French macrophage (1887), and microphage n.

Medicine.

A mononuclear phagocytic cell of monocytic lineage, widely distributed throughout the body in both stationary and mobile forms, which is involved in many aspects of immune function and regulation.

ΘΚΠ

the world > life > biology > substance > cell > types of cells > [noun] > phagocytic cells > leucocyte or lymphocyte

cytoid1850

leucocyte1870

cytode1883

macrophage1887

lymphocyte1890

memory cell1892

macrophagocyte1896

lymphoblast1909

thymocyte1929

siderophage1941

Sézary cells1953

the world > life > the body > vascular system > blood > components of blood > blood corpuscle or plate > [noun] > white cells or corpuscles

white corpuscle1823

white cell1852

leucocyte1870

phagocyte1884

macrophage1887

microphage1887

lymphocyte1890

megakaryocyte1890

hyaline cell1894

macrophagocyte1896

microphagocyte1896

scavenger-cell1899

splenocyte1900

polymorph1902

granulocyte1906

lymphoblast1909

agranulocyte1913

monocyte1913

stab1929

hyaline leucocyte1931

smudge cell1937

heterophile1938

siderophage1941

1887 Lancet 5 Mar. 483/1 The phenomena of local infection, inflammatory reaction, resolution, and absorption of the inflammatory products, can all be expressed in the terms of streptococcus, microphage, and macrophage.

1897 T. C. Allbutt et al. Syst. Med. II. 7 These macrophages can destroy the tubercle bacilli.

1937 Amer. Jrnl. Cancer 29 666 Pinocytosis (drinking) by macrophages in tissue cultures is common.

1959 F. M. Burnet Clonal Select. Theory Acquired Immunity vii. 115 Macrophages..include fixed macrophages, wandering tissue macrophages..and the blood monocytes.

1984 J. F. Lamb et al. Essent. Physiol. (ed. 2) iv. 67 At the end of their lives the erythrocytes are destroyed by the scavenger cells of the liver (macrophages or Kupffer cells).

1990 Times 15 Nov. 20/3 Lysteriolysin, the toxin produced by the listeria bacteria, acts by damaging macrophages.

Compounds

macrophage activating factor n. a lymphokine or other factor that enhances the function of macrophages; cf. MAF n. at M n. Initialisms 1.

ΘΚΠ

the world > life > biology > substance > process stimulators or inhibitors > antibody > [noun] > lymphokine

lymphokine1969

macrophage activating factor1974

macrophage activation factor1984

1974 Jrnl. Immunol. 112 502/1 It was not possible to distinguish between production of CSF by activated lymphocytes or production of a macrophage activating factor.

1992 Saudi Med. Jrnl. 12 451/2 Increased bactericidal activity of the infected macrophages can be induced by IFNγ, which we know is a principal ‘macrophage activating factor’ (MAF).

macrophage activation factor n. = macrophage activating factor n.

ΘΚΠ

the world > life > biology > substance > process stimulators or inhibitors > antibody > [noun] > lymphokine

lymphokine1969

macrophage activating factor1974

macrophage activation factor1984

1984 M. J. Taussig Processes in Pathol. & Microbiol. (ed. 2) i. 62 Chief among them are macrophage migration inhibition factor (MIF), which causes the immobilisation of macrophages at the site of reaction, and macrophage activation factor (MAF), which induces their activation into cells which can kill and destroy their ingested micro-organisms, and their transformation into epithelioid cells.

macrophage colony-stimulating factor n. a cytokine that stimulates the proliferation and differentiation of monocytes and macrophages; cf. M-CSF n. at M n. Initialisms 1.

ΘΚΠ

the world > life > biology > substance > process stimulators or inhibitors > antibody > [noun] > proteins aiding antibodies

addiment1900

complement1900

macrophage colony-stimulating factor1978

M-CSF1978

1978 Jrnl. Cell Biol. 77 35 (title) Molecular and biological properties of a macrophage colony-stimulating factor from mouse yolk sacs.

1988 BioFactors 1 167/1 It has been reported that macrophage colony-stimulating factor (M-CSF) is secreted from mouse L-cells.

1989 N.Y. Times 23 Sept. 32/5 Genetics Institute Inc...received a patent covering the genetic instructions to make a hormone called Macrophage Colony Stimulating factor, or M-CSF.

1998 DNA & Cell Biol. 17 799 Macrophage colony-stimulating factor (M-CSF; CSF-1) is a member of a complex network of cytokines that regulate monocytic cell development and activity. It is produced in nearly all organs by cell types commonly found in connective tissue, including fibroblasts and monocytes.

Derivatives

macroˈphagic adj.

ΘΚΠ

the world > life > biology > substance > cell > types of cells > [adjective] > phagocytic cells > leucocyte or lymphocyte

cytoid1853

lymphocytic1896

macrophagic1904

lymphoblastic1905

littoral1930

neutrophil1930

the world > life > the body > vascular system > blood > components of blood > blood corpuscle or plate > [adjective] > white cells or corpuscles

leucocytal1879

leucocytic1879

phagocytic1887

phagocytical1890

lymphocytic1896

leucocytary1900

lymphogenic1901

macrophagic1904

lymphoblastic1905

lymphopoietic1915

megakaryocytic1925

monocytic1927

1904 Brit. Med. Jrnl. 10 Sept. 562/1 The lymph glands and other macrophagic organs.

1971 Nature 5 Feb. 412/2 A sparse scattering of cells, presumably macrophagic or inflammatory.

1991 Hematol. Oncol. 9 128 The monocytopenia and defective monocytic-macrophagic function characteristic of overt HCL would..be the determining factors.

This entry has been updated (OED Third Edition, March 2000; most recently modified version published online March 2022).

单词	macrophage
释义	macrophagen. Brit. /ˈmakrə(ʊ)feɪdʒ/, U.S. /ˈmækrəˌfeɪdʒ/ Origin: Formed within English, by compounding; modelled on a German lexical item. Etymons: macro- comb. form, -phage comb. form. Etymology: < macro- comb. form + -phage comb. form, after German Makrophagen (plural; E. Metschnikoff 1887, in Arch. f. Pathol. Anat. u. Physiol. 107 222). Compare French macrophage (1887), and microphage n. Medicine. A mononuclear phagocytic cell of monocytic lineage, widely distributed throughout the body in both stationary and mobile forms, which is involved in many aspects of immune function and regulation. ΘΚΠ the world > life > biology > substance > cell > types of cells > [noun] > phagocytic cells > leucocyte or lymphocyte cytoid1850 leucocyte1870 cytode1883 macrophage1887 lymphocyte1890 memory cell1892 macrophagocyte1896 lymphoblast1909 thymocyte1929 siderophage1941 Sézary cells1953 the world > life > the body > vascular system > blood > components of blood > blood corpuscle or plate > [noun] > white cells or corpuscles white corpuscle1823 white cell1852 leucocyte1870 phagocyte1884 macrophage1887 microphage1887 lymphocyte1890 megakaryocyte1890 hyaline cell1894 macrophagocyte1896 microphagocyte1896 scavenger-cell1899 splenocyte1900 polymorph1902 granulocyte1906 lymphoblast1909 agranulocyte1913 monocyte1913 stab1929 hyaline leucocyte1931 smudge cell1937 heterophile1938 siderophage1941 1887 Lancet 5 Mar. 483/1 The phenomena of local infection, inflammatory reaction, resolution, and absorption of the inflammatory products, can all be expressed in the terms of streptococcus, microphage, and macrophage. 1897 T. C. Allbutt et al. Syst. Med. II. 7 These macrophages can destroy the tubercle bacilli. 1937 Amer. Jrnl. Cancer 29 666 Pinocytosis (drinking) by macrophages in tissue cultures is common. 1959 F. M. Burnet Clonal Select. Theory Acquired Immunity vii. 115 Macrophages..include fixed macrophages, wandering tissue macrophages..and the blood monocytes. 1984 J. F. Lamb et al. Essent. Physiol. (ed. 2) iv. 67 At the end of their lives the erythrocytes are destroyed by the scavenger cells of the liver (macrophages or Kupffer cells). 1990 Times 15 Nov. 20/3 Lysteriolysin, the toxin produced by the listeria bacteria, acts by damaging macrophages. Compounds macrophage activating factor n. a lymphokine or other factor that enhances the function of macrophages; cf. MAF n. at M n. Initialisms 1. ΘΚΠ the world > life > biology > substance > process stimulators or inhibitors > antibody > [noun] > lymphokine lymphokine1969 macrophage activating factor1974 macrophage activation factor1984 1974 Jrnl. Immunol. 112 502/1 It was not possible to distinguish between production of CSF by activated lymphocytes or production of a macrophage activating factor. 1992 Saudi Med. Jrnl. 12 451/2 Increased bactericidal activity of the infected macrophages can be induced by IFNγ, which we know is a principal ‘macrophage activating factor’ (MAF). macrophage activation factor n. = macrophage activating factor n. ΘΚΠ the world > life > biology > substance > process stimulators or inhibitors > antibody > [noun] > lymphokine lymphokine1969 macrophage activating factor1974 macrophage activation factor1984 1984 M. J. Taussig Processes in Pathol. & Microbiol. (ed. 2) i. 62 Chief among them are macrophage migration inhibition factor (MIF), which causes the immobilisation of macrophages at the site of reaction, and macrophage activation factor (MAF), which induces their activation into cells which can kill and destroy their ingested micro-organisms, and their transformation into epithelioid cells. macrophage colony-stimulating factor n. a cytokine that stimulates the proliferation and differentiation of monocytes and macrophages; cf. M-CSF n. at M n. Initialisms 1. ΘΚΠ the world > life > biology > substance > process stimulators or inhibitors > antibody > [noun] > proteins aiding antibodies addiment1900 complement1900 macrophage colony-stimulating factor1978 M-CSF1978 1978 Jrnl. Cell Biol. 77 35 (title) Molecular and biological properties of a macrophage colony-stimulating factor from mouse yolk sacs. 1988 BioFactors 1 167/1 It has been reported that macrophage colony-stimulating factor (M-CSF) is secreted from mouse L-cells. 1989 N.Y. Times 23 Sept. 32/5 Genetics Institute Inc...received a patent covering the genetic instructions to make a hormone called Macrophage Colony Stimulating factor, or M-CSF. 1998 DNA & Cell Biol. 17 799 Macrophage colony-stimulating factor (M-CSF; CSF-1) is a member of a complex network of cytokines that regulate monocytic cell development and activity. It is produced in nearly all organs by cell types commonly found in connective tissue, including fibroblasts and monocytes. Derivatives macroˈphagic adj. ΘΚΠ the world > life > biology > substance > cell > types of cells > [adjective] > phagocytic cells > leucocyte or lymphocyte cytoid1853 lymphocytic1896 macrophagic1904 lymphoblastic1905 littoral1930 neutrophil1930 the world > life > the body > vascular system > blood > components of blood > blood corpuscle or plate > [adjective] > white cells or corpuscles leucocytal1879 leucocytic1879 phagocytic1887 phagocytical1890 lymphocytic1896 leucocytary1900 lymphogenic1901 macrophagic1904 lymphoblastic1905 lymphopoietic1915 megakaryocytic1925 monocytic1927 1904 Brit. Med. Jrnl. 10 Sept. 562/1 The lymph glands and other macrophagic organs. 1971 Nature 5 Feb. 412/2 A sparse scattering of cells, presumably macrophagic or inflammatory. 1991 Hematol. Oncol. 9 128 The monocytopenia and defective monocytic-macrophagic function characteristic of overt HCL would..be the determining factors. This entry has been updated (OED Third Edition, March 2000; most recently modified version published online March 2022). < n.1887
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