malondialdehyden.
/ˌmaləndʌɪˈaldᵻhʌɪd/, U.S. /ˌmæləndaɪˈældəhaɪd/ Chemistry.
The aldehyde, CH2(CHO)2, of malonic acid, which occurs naturally as a breakdown product of lipid hydroperoxides and has mutagenic and cytotoxic properties owing to its ability to cross-link various molecules.
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the world > matter > chemistry > organic chemistry > aldehydes or alkanals > [noun] > miscellaneous named aldehydes > others
acrolein1841
metaldehyde1841
trichlorocetaldehyde1845
valeral1852
toluic aldehyde1857
glyoxal1858
acraldehyde1864
propionic aldehyde1866
lauric aldehyde, ether1868
salicylaldehyde1869
dialdane1876
isovaleraldehyde1883
rhodinal1892
propenal1894
oxaldehyde1895
methylglyoxal1898
hadromal1899
malondialdehyde1904
pyruvic aldehyde1909
trioxan1915
plasmal1925
1904 Jrnl. Chem. Soc. 86 14 The Β-ethoxy-acetal, when shaken with water, loses a molecule of alcohol and yields malondialdehyde.
1982 T. M. Devlin Textbk. Biochem. ix. 483 The lipid hydroperoxide molecules break up, forming dialdehydes, the most prominent being malondialdehyde.
1987 D. J. Betteridge in K. G. Taylor Diabetes & Heart (BNC) 98 Forty-one per cent of these diabetics had levels of malondialdehyde formation greater than the highest result seen in the control group.
1997 Clin. Chim. Acta 263 177 The measurement of malondialdehyde (MDA) in biological fluids remains a popular method for the quantification of free radical damage to lipids in vivo.
This is a new entry (OED Third Edition, June 2000; most recently modified version published online March 2022).
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n.1904