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单词 marzine
释义

Marzinen.

Brit. /ˈmɑːziːn/, U.S. /ˈmɑrˌzin/
Origin: A variant or alteration of another lexical item. Etymon: Marezine n.
Etymology: Altered form of Marezine n.
Pharmacology.
An anti-emetic drug used to treat motion sickness and vertigo, consisting of cyclizine hydrochloride, a piperazine derivative, or (in later use) the related compound cinnarizine, C26H28N2. Cf. Marezine n.A proprietary name in the United Kingdom.
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the world > health and disease > healing > medicines or physic > medicines for specific purpose > astringent or restringent preparations > [noun] > for stopping vomiting or nausea > specific drugs
Phenergan1948
Dramamine1949
promethazine1949
chlorpromazine1952
Marezine1952
Marzine1954
Thorazine1954
meclozine1955
perphenazine1957
trifluoperazine1958
metoclopramide1964
sulpiride1970
1954 Trade Marks Jrnl. 24 Mar. 297/1 Marzine... All goods included in class 5 [pharmaceutical, veterinary, and sanitary substances, etc.]. The Wellcome Foundation Limited,..London,..manufacturing chemists.
1959 Lancet 25 Apr. 853/1 Cyclizine hydrochloride (‘Marezine’, ‘Marzine’) in doses of 50 mg. daily was also found effective [in motion sickness].
1967 Med., Sci. & Law 7 201/2 All five subjects showed no significant difference between their driving performance when taking the placebo or Marzine.
1989 Martindale's Extra Pharmacopoeia (ed. 29) 451/1 The UK preparation Marzine now contains cinnarizine instead of cyclizine.
This entry has been updated (OED Third Edition, December 2000; most recently modified version published online March 2022).
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n.1954
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