medulloblastoman.
/mɛˌdʌləʊblaˈstəʊmə/, /mᵻˌdʌləʊblaˈstəʊmə/, U.S. /məˌdəloʊˌblæˈstoʊmə/, /ˌmɛdʒəloʊˌblæˈstoʊmə/ Pathology.
A malignant tumour of neuroectodermal origin, most commonly found in the vermis of the cerebellum in children.
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the world > health and disease > ill health > a disease > disorders of internal organs > disorders of nervous system > [noun] > disorders of brain > brain tumour
testudoc1400
Talpa1684
glioma1870
psammoma1872
myxoglioma1878
gliomatosis1886
gliosis1892
cephalhaematoma1900
meningioma1922
medulloblastoma1925
glioblastoma multiforme1926
space-occupying lesion1937
neuroglioblastoma1985
1925 P. Bailey & H. Cushing in Arch. Neurol. & Psychiatry (Chicago) 14 193 We shall adopt for our cases the term Medulloblastoma as appropriate to the particular tumors to which we independently wish to call attention.
1926 P. Bailey & H. Cushing Classif. Tumors Glioma Group 118 Medullo~blastomas..are rapidly growing, soft, malignant tumors which not infrequently, when they reach the leptomeninges, disseminate themselves through the subarachnoid spaces.
1957 Brit. Jrnl. Radiol. 30 590 (title) Cerebrospinal irradiation for medulloblastoma.
1974 R. Passmore & J. S. Robson Compan. Med. Stud. III. xxxiv. 75/1 Medulloblastomata usually arise from the inferior vermis and involve the flocculus and nodule. Hence the presentation is often difficulty in walking, truncal ataxia and a tendency to sudden falls.
1984 M. J. Taussig Processes in Pathol. & Microbiol. (ed. 2) vii. 875 Some of the common neoplasms which recur in families in non-Mendelian fashion include..neuroblastoma and medulloblastoma.
2000 Nature 31 Aug. 1005/1 Basal cell carcinoma, medulloblastoma, rhabdomyosarcoma and other human tumours are associated with mutations that activate the proto-oncogene Smoothened (SMO) or that inactivate the tumour suppressor Patched (PTCH).
This entry has been updated (OED Third Edition, June 2001; most recently modified version published online March 2022).
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