mebutamaten.

Brit.

/məˈbjuːtəmeɪt/, U.S.

/məˈbjudəˌmeɪt/

Origin: Formed within English, by compounding. Etymons: methyl n., butyl n., carbamate n. at carbamide n. Derivatives

Etymology: < me- (in methyl n.) + but- (in butyl n.) + -amate (in carbamate n. at carbamide n. Derivatives), probably after meprobamate n.

Pharmacology.

A compound with sedative and anti-hypertensive properties, administered orally in the treatment of hypertension; 2-sec-butyl-2-methyltrimethylene dicarbamate, C₁₀H₂₀N₂O₄.

ΚΠ

1961 New Scientist 21 Sept. 702/3 The best way of attempting to treat hypertension would appear to be to damp down the impulses emanating from this [vasomotor] centre. This can now be done by means of the drug mebutamate, which was discovered by Dr. F. M. Berger and his colleagues.

1967 Canad. Med. Assoc. Jrnl. 97 397/2 Mebutamate, a drug with a chemical structure analogous to that of meprobamate, possesses interesting hypnotic properties at doses which we used, 600 and 800 mg.

1972 Materials & Technol. V. xxi. 791 Mebutamate, a derivative of the tranquilliser meprobamate, and hydrallazine directly reduce the vasomotor centre activity.

This is a new entry (OED Third Edition, June 2001; most recently modified version published online March 2022).

单词	mebutamate
释义	mebutamaten. Brit. /məˈbjuːtəmeɪt/, U.S. /məˈbjudəˌmeɪt/ Origin: Formed within English, by compounding. Etymons: methyl n., butyl n., carbamate n. at carbamide n. Derivatives Etymology: < me- (in methyl n.) + but- (in butyl n.) + -amate (in carbamate n. at carbamide n. Derivatives), probably after meprobamate n. Pharmacology. A compound with sedative and anti-hypertensive properties, administered orally in the treatment of hypertension; 2-sec-butyl-2-methyltrimethylene dicarbamate, C₁₀H₂₀N₂O₄. ΚΠ 1961 New Scientist 21 Sept. 702/3 The best way of attempting to treat hypertension would appear to be to damp down the impulses emanating from this [vasomotor] centre. This can now be done by means of the drug mebutamate, which was discovered by Dr. F. M. Berger and his colleagues. 1967 Canad. Med. Assoc. Jrnl. 97 397/2 Mebutamate, a drug with a chemical structure analogous to that of meprobamate, possesses interesting hypnotic properties at doses which we used, 600 and 800 mg. 1972 Materials & Technol. V. xxi. 791 Mebutamate, a derivative of the tranquilliser meprobamate, and hydrallazine directly reduce the vasomotor centre activity. This is a new entry (OED Third Edition, June 2001; most recently modified version published online March 2022). < n.1961
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