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单词 mecamylamine
释义

mecamylaminen.

Brit. /ˌmɛkəˈmʌɪləmiːn/, U.S. /ˌmɛkəˈmaɪləˌmin/
Origin: Formed within English, by derivation. Etymons: methyl n., camphane n. at camph- comb. form , -yl suffix, amine n.
Etymology: < me- (in methyl n.) + cam- (in camphane n. at camph- comb. form ) + -yl suffix + amine n.
Pharmacology.
A norbornane derivative which is a ganglionic nicotinic blocking agent, sometimes used in treating extreme hypertension; N,2,3,3-tetramethylbicyclo[2.2.1]hept-2-ylamine, C11H21N.
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the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations treating or preventing specific ailments > [noun] > for blood-pressure disorders
Neo-Synephrine1934
Priscol1938
phenylephrine1947
hexamethonium1949
Priscoline1949
methonium1950
hydralazine1952
phentolamine1953
methyldopa1954
pentolinium1954
mecamylamine1955
hydrochlorothiazide1958
pempidine1958
guanethidine1959
hydroflumethiazide1959
thiazide1959
pheniprazine1960
pargyline1961
vasodepressor1961
alpha blocker1965
clonidine1969
prazosin1970
timolol1973
1955 Sci. News Let. 29 Oct. 281/1 A nerve-blocking drug called mecamylamine.
1968 L. Gyermek in A. Burger Drugs affecting Central Nerv. Syst. I. iv. 290 Mecamylamine depresses the vasomotor center independently of its ganglionic blocking action.
1974 M. C. Gerald Pharmacol. viii. 159 Ganglionic blocking agents such as mecamylamine (Inversine)..prevent cholinergic transmission at the autonomic ganglia.
1989 Jrnl. Psychopharmacol. 3 90/2 The small and large doses of mecamylamine were chosen to produce partial and full block of the nicotine cue respectively.
This entry has been updated (OED Third Edition, June 2001; most recently modified version published online March 2022).
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n.1955
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