melphalann.

Brit.

/ˈmɛlfəlan/, U.S.

/ˈmɛlfəˌlæn/

Origin: Formed within English, by compounding. Etymons: methyl n., L n. Initialisms 3c, phenylalanine n.

Etymology: < me- (in methyl n.) + L n. Initialisms 3c + ph- and -alan- (in phenylalanine n.).

Pharmacology.

A nitrogen mustard given orally and intravenously in the treatment of multiple myeloma and other neoplasms; 4-bis(2-chloroethyl)amino- l-phenylalanine, C₁₃H₁₈Cl₂N₂O₂.

ΘΚΠ

the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations treating or preventing specific ailments > [noun] > for tumour

platinum blue1908

nitrogen mustard1943

mustard1945

piperoxan1950

melphalan1960

procarbazine1965

bleomycin1966

1960 Cancer Chemotherapy Rep. Feb. 61 Melphalan.

1962 Surgery 51 583/1 Phenylalanine mustard exists in two forms. One is the dl form called Sarcolysin; the other is the l form called melphelan [sic].

1974 R. M. Kirk et al. Surgery v. 73 When excision is not possible..it is worth trying the effects of..systemic chemotherapy with phenylalanine mustard drugs, or melphalan given systemically.

1993 S. J. Ettinger Pocket Compan. Textbk. Vet. Internal Med. cxix. 779 Melphalan has been and continues to be the antineoplastic drug of choice.

This entry has been updated (OED Third Edition, June 2001; most recently modified version published online March 2022).

单词	melphalan
释义	melphalann. Brit. /ˈmɛlfəlan/, U.S. /ˈmɛlfəˌlæn/ Origin: Formed within English, by compounding. Etymons: methyl n., L n. Initialisms 3c, phenylalanine n. Etymology: < me- (in methyl n.) + L n. Initialisms 3c + ph- and -alan- (in phenylalanine n.). Pharmacology. A nitrogen mustard given orally and intravenously in the treatment of multiple myeloma and other neoplasms; 4-bis(2-chloroethyl)amino- l-phenylalanine, C₁₃H₁₈Cl₂N₂O₂. ΘΚΠ the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations treating or preventing specific ailments > [noun] > for tumour platinum blue1908 nitrogen mustard1943 mustard1945 piperoxan1950 melphalan1960 procarbazine1965 bleomycin1966 1960 Cancer Chemotherapy Rep. Feb. 61 Melphalan. 1962 Surgery 51 583/1 Phenylalanine mustard exists in two forms. One is the dl form called Sarcolysin; the other is the l form called melphelan [sic]. 1974 R. M. Kirk et al. Surgery v. 73 When excision is not possible..it is worth trying the effects of..systemic chemotherapy with phenylalanine mustard drugs, or melphalan given systemically. 1993 S. J. Ettinger Pocket Compan. Textbk. Vet. Internal Med. cxix. 779 Melphalan has been and continues to be the antineoplastic drug of choice. This entry has been updated (OED Third Edition, June 2001; most recently modified version published online March 2022). < n.1960
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