单词 | melanoderma |
释义 | melanoderman. Medicine. Any of various conditions characterized by patchy or diffuse darkening of the skin. ΚΠ 1867 E. Wilson On Dis. Skin (ed. 6) xx. 681 The more common change is that of a deepening in hue of the natural dark pigment of the rete mucosum, constituting melanopathia, melanoderma, or melasma. 1901 W. Osler Princ. & Pract. Med. (ed. 4) viii. 831 Lastly, with arterio-sclerosis and chronic heart-disease there may be marked melanoderma. 1949 H. W. C. Vines Green's Man. Pathol. (ed. 17) xxxii. 869 Pigmentation of the skin, or melanoderma, is a fairly constant sign [in Addison's disease] affecting the mucous membrane of the mouth or vagina, giving rise to brown or black patches. 1996 Brit. Jrnl. Dermatol. 134 325 Since 1975, two of 745 patients treated by allogeneic bone marrow transplantation in our institution have developed diffuse melanoderma which differed considerably from the classic presentations. This entry has been updated (OED Third Edition, June 2001; most recently modified version published online March 2022). < n.1867 |
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